Spontaneously Blinking Rhodamine Dyes for Single-Molecule Localization Microscopy

被引：32
作者：
Chi, Weijie [1 ,2 ]
Tan, Davin [2 ]
Qiao, Qinglong [3 ]
Xu, Zhaochao [3 ]
Liu, Xiaogang [2 ]
机构：
[1] Hainan Univ, Collaborat Innovat Ctr One Hlth, Sch Sci, Renmin Rd 58, Haikou 570228, Peoples R China
[2] Singapore Univ Technol & Design, Fluorescence Res Grp, 8 Somapah Rd, Singapore 487372, Singapore
[3] Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, 457 Zhongshan Rd, Dalian 116023, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2023年 / 62卷 / 39期
基金：
海南省自然科学基金; 中国国家自然科学基金;
关键词：
Rhodamine Dyes; Single-Molecule Localization Microscopy; Spirocyclization Equilibrium; Spontaneously Blinking Fluorophores; INTRAMOLECULAR SPIROCYCLIZATION; LIVE-CELL; SUPERRESOLUTION; FLUOROPHORES;
D O I：
10.1002/anie.202306061
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Single-molecule localization microscopy (SMLM) has found extensive applications in various fields of biology and chemistry. As a vital component of SMLM, fluorophores play an essential role in obtaining super-resolution fluorescence images. Recent research on spontaneously blinking fluorophores has greatly simplified the experimental setups and extended the imaging duration of SMLM. To support this crucial development, this review provides a comprehensive overview of the development of spontaneously blinking rhodamines from 2014 to 2023, as well as the key mechanistic aspects of intramolecular spirocyclization reactions. We hope that by offering insightful design guidelines, this review will contribute to accelerating the advancement of super-resolution imaging technologies.
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页数：14
相关论文
共 42 条
[1]   Microscopic imaging techniques for drug discovery [J].
Bullen, Andrew .
NATURE REVIEWS DRUG DISCOVERY, 2008, 7 (01) :54-67
[2]   A unified fluorescence quenching mechanism of tetrazine-based fluorogenic dyes: energy transfer to a dark state [J].
Chi, Weijie ;
Huang, Lu ;
Wang, Chao ;
Tan, Davin ;
Xu, Zhaochao ;
Liu, Xiaogang .
MATERIALS CHEMISTRY FRONTIERS, 2021, 5 (18) :7012-7021
[3]   Descriptor ΔGC-OEnables the Quantitative Design of Spontaneously Blinking Rhodamines for Live-Cell Super-Resolution Imaging [J].
Chi, Weijie ;
Qiao, Qinglong ;
Wang, Chao ;
Zheng, Jiazhu ;
Zhou, Wei ;
Xu, Ning ;
Wu, Xia ;
Jiang, Xiao ;
Tan, Davin ;
Xu, Zhaochao ;
Liu, Xiaogang .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 59 (45) :20215-20223
[4]   A Unified Push-Pull Model for Understanding the Ring-Opening Mechanism of Rhodamine Dyes [J].
Chi, Weijie ;
Qi, Qingkai ;
Lee, Richmond ;
Xu, Zhaochao ;
Liu, Xiaogang .
JOURNAL OF PHYSICAL CHEMISTRY C, 2020, 124 (06) :3793-3801
[5]  
Dempsey GT, 2011, NAT METHODS, V8, P1027, DOI [10.1038/nmeth.1768, 10.1038/NMETH.1768]
[6]   Blinking Fluorescent Probes for Tubulin Nanoscopy in Living and Fixed Cells [J].
Gerasimaite, Ruta ;
Bucevicius, Jonas ;
Kiszka, Kamila A. ;
Schnorrenberg, Sebastian ;
Kostiuk, Georgij ;
Koenen, Tanja ;
Lukinavicius, Grazvydas .
ACS CHEMICAL BIOLOGY, 2021, 16 (11) :2130-2136
[7]   Machine learning approaches to understand and predict rate constants for organic processes in mixtures containing ionic liquids [J].
Greaves, Tamar L. ;
Schaffarczyk McHale, Karin S. ;
Burkart-Radke, Raphael F. ;
Harper, Jason B. ;
Le, Tu C. .
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 23 (04) :2742-2752
[8]  
Grimm JB, 2017, NAT METHODS, V14, P987, DOI [10.1038/NMETH.4403, 10.1038/nmeth.4403]
[9]   Effects of Amino Group Substitution on the Photophysical Properties and Stability of Near-Infrared Fluorescent P-Rhodamines [J].
Grzybowski, Marek ;
Taki, Masayasu ;
Kajiwara, Keiji ;
Yamaguchi, Shigehiro .
CHEMISTRY-A EUROPEAN JOURNAL, 2020, 26 (35) :7912-7917
[10]   A Mitochondrion-Specific Photoactivatable Fluorescence Turn-On AIE-Based Bioprobe for Localization Super-Resolution Microscope [J].
Gu, Xinggui ;
Zhao, Engui ;
Zhao, Teng ;
Kang, Miaomiao ;
Gui, Chen ;
Lam, Jacky W. Y. ;
Du, Shengwang ;
Loy, Michael M. T. ;
Tang, Ben Zhong .
ADVANCED MATERIALS, 2016, 28 (25) :5064-5071
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