Nanoparticle-based theranostics in nuclear medicine

被引：4

作者：

Uinarni, Herlina ^{[1
,2
]}

Kadhum, Wesam R. ^{[3
,4
]}

Saleh, Raed Obaid ^{[5
]}

Alawadi, Ahmed ^{[6
,7
,8
]}

Alnajar, Mohammed Jawad ^{[9
]}

Shalaby, Nagat Salah ^{[10
]}

Alkhafaji, Adnan Taan ^{[11
]}

Kumar, Abhinav ^{[12
]}

Sahib, Rasha Salam ^{[13
]}

Mustafa, Yasser Fakri ^{[14
]}

机构：

[1] Atma Jaya Catholic Univ Indonesia, Sch Med & Hlth Sci, Dept Anat, Jakarta, Indonesia

[2] Indah Kapuk Hosp, Radiol Dept Pantai, Jakarta, Indonesia

[3] Kut Univ Coll, Dept Pharm, Kut 52001, Wasit, Iraq

[4] Kut Univ Coll, Adv Res Ctr, Kut 52001, Wasit, Iraq

[5] Al Maarif Univ Coll, Dept Med Lab Tech, Al Anbar, Iraq

[6] Islamic Univ, Coll Tech Engn, Najaf, Iraq

[7] Islamic Univ Al Diwaniyah, Coll Tech Engn, Al Diwaniyah, Iraq

[8] Islamic Univ Babylon, Coll Tech Engn, Babylon, Iraq

[9] Al Nisour Univ Coll, Anesthesia Tech, Baghdad, Iraq

[10] Natl Univ Sci & Technol, Coll Nursing, Nasiriyah, Dhi Qar, Iraq

[11] Al Ayen Univ, Coll Med, Cardiol Dept, Nasiriyah, Dhi Qar, Iraq

[12] Ural Fed Univ, Dept Nucl & Renewable Energy, Ekaterinburg 620002, Russia

[13] Al Rafidain Univ Coll, Dept Med Lab Technol, Baghdad, Iraq

[14] Univ Mosul, Coll Pharm, Dept Pharmaceut Chem, Mosul 41001, Iraq

来源：

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | 2024年 / 333卷 / 04期

关键词：

Nanoparticle; Theranostic; Nuclear medicine; Imaging; Treatment; ENTRAPPED GOLD NANOPARTICLES; DRUG-DELIVERY; SILICA NANOPARTICLES; FUTURE; NANOCARRIERS; NANOTHERANOSTICS; NANOMEDICINE; THERAPEUTICS; LIPOSOMES; TOXICITY;

D O I：

10.1007/s10967-024-09432-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Nuclear medicine has revolutionized medical diagnostic and therapeutic interventions by employing radiopharmaceuticals for detection and treatment. However, the limited selectivity and efficacy of traditional radiopharmaceuticals call for novel approaches to enhance the precision and therapeutic potential of nuclear medicine. Application of nanoparticle-mediated radiopharmaceuticals in treatment and diagnostics (theranostics) integrates imaging and therapeutic modalities into a single nanoscale platform to address these challenges and open new insights. This review study comprehensively explores the recent improvements in nanoparticle-based theranostics for nuclear medicine applications. In this regard, the fundamentals of nuclear medicine and the significance of combining imaging and therapy are introduced. Moreover, in this context, we evaluated the challenges of nanoparticle-based theranostics, especially from the viewpoint of toxicity and immunogenicity.

引用

页码：1661 / 1672

页数：12

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