Advances in the application of label-free quantitative proteomics techniques in malignancy research

被引：2
作者：
Meng, Xiao [1 ]
Liu, Dong [1 ]
Guan, Yan [1 ]
机构：
[1] Weifang Med Univ, Sch Med Lab, 7166 Baotong West St, Weifang 261053, Shandong, Peoples R China
来源：
BIOMEDICAL CHROMATOGRAPHY | 2023年 / 37卷 / 07期
关键词：
data-independent acquisition; label free; malignant tumors; proteomics; sequential window acquisition of all theoretical mass spectra; NASOPHARYNGEAL CARCINOMA; GASTRIC-CANCER; ELECTROPHORESIS; IDENTIFICATION; PROTEINS;
D O I：
10.1002/bmc.5667
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Proteomics is the scientific discipline that deals with the protein composition of cells, tissues, and organisms and their patterns of change. It is considered an invaluable tool for tackling many challenges faced in medicine and biology. Among the available approaches, label-free quantitative proteomics techniques are extensively used to study malignant tumors due to their low cost, simple operation, and short cycle time. Therefore, it provides a novel approach to explore the pathogenesis, diagnostic markers, and targeted drugs of malignant tumors. Here, we summarize the research progress and potential of label-free quantitative proteomics and discuss the application of such techniques in the research on malignancies.
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页数：11
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