Testicular teratoma with nephroblastoma in an adult-case report and literature review

Testicular germ cell tumours are the most common malignancies in young men. Germ cell tumours can be classified as seminomas or non-sem-inomas, each with different clinical features and treatment approaches. Germ cell tumours are occasionally associated with somatic-type malig-nancy, particularly in metastatic lymph nodes after adjuvant chemotherapy. Adenocarcinomas and rhabdomyosar-coma are the most common malignan-cies in this setting. In this report, we present a unique case of a 37-year-old patient who presented with a testic-ular teratoma containing a nephro-blastoma component. The tumour exhibited characteristic morphology that resembled foetal kidney and ex-pressed nuclear WT-1 and PAX-8 on immunohistochemistry. Following sur-gery, the patient opted for active sur-veillance and remains disease-free. To date, only 7 cases of nephroblastoma in primary testicular teratoma have been reported. This case highlights the importance of considering this rare entity in the differential diagnosis of testicular teratomas and the need for careful pathological examination.