Mitophagy, Inflammasomes and Their Interaction in Kidney Diseases: A Comprehensive Review of Experimental Studies

被引：5
作者：
Wang, Yulin [1 ]
Song, Dongxu [1 ]
Tang, Lin [1 ,2 ]
机构：
[1] Zhengzhou Univ, Dept Nephrol, Affiliated Hosp 1, Zhengzhou 450052, Henan, Peoples R China
[2] Zhengzhou Univ, Dept Nephrol, Affiliated Hosp 1, 1 Jianshe Rd, Zhengzhou 450052, Henan, Peoples R China
来源：
JOURNAL OF INFLAMMATION RESEARCH | 2023年 / 16卷
基金：
中国国家自然科学基金;
关键词：
mitophagy; inflammasomes; kidney diseases; acute kidney injury; chronic kidney disease; diabetic kidney disease; RENAL TUBULAR INJURY; NLRP3; INFLAMMASOME; MITOCHONDRIAL DYSFUNCTION; DIABETIC-NEPHROPATHY; ACTIVATION; PROTECTS; PARKIN; MECHANISMS; CELLS; DISTURBANCES;
D O I：
10.2147/JIR.S402290
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Mitophagy is an important mechanism for mitochondrial quality control by regulating autophagosome-specific phagocy-tosis, degradation and clearance of damaged mitochondria, and involved in cell damage and diseases. Inflammasomes are important inflammation-related factors newly discovered in recent years, which are involved in cell innate immunity and inflammatory response, and play an important role in kidney diseases. Based on the current studies, we reviewed the progress of mitophagy, inflammasomes and their interaction in kidney diseases.
引用
收藏
页码：1457 / 1469
页数：13
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