The Antibacterial and Wound Healing Properties of Natural Products: A Review on Plant Species with Therapeutic Potential against Staphylococcus aureus Wound Infections

被引：13

作者：

Morguette, Ana Elisa Belotto ^{[1
]}

Bartolomeu-Goncalves, Guilherme ^{[2
]}

Andriani, Gabriella Maria ^{[1
]}

Bertoncini, Giovana Elika Silveira ^{[3
]}

de Castro, Isabela Madeira ^{[1
]}

Spoladori, Lais Fernanda de Almeida ^{[1
]}

Bertao, Ariane Mayumi Saito ^{[4
]}

Tavares, Eliandro Reis ^{[3
]}

Yamauchi, Lucy Megumi ^{[1
,3
]}

Yamada-Ogatta, Sueli Fumie ^{[1
,2
,3
]}

机构：

[1] Univ Estadual Londrina, Ctr Ciencias Biol, Dept Microbiol, Programa Pos Grad Microbiol, BR-86057970 Londrina, PR, Brazil

[2] Univ Estadual Londrina, Programa Pos Grad Fisiopatol Clin & Lab, BR-86038350 Londrina, PR, Brazil

[3] Univ Estadual Londrina, Lab Biol Mol Microrganismos, BR-86057970 Londrina, PR, Brazil

[4] Ctr Univ Filadelfia, BR-86010520 Londrina, PR, Brazil

来源：

PLANTS-BASEL | 2023年 / 12卷 / 11期

关键词：

antibacterial activity; herbal products; methicillin-resistant Staphylococcus aureus; wound healing; wound infection; ANTIINFLAMMATORY ACTIVITIES; ANTIOXIDANT ACTIVITIES; ESSENTIAL OIL; L; EXTRACT; KERATINOCYTES; PATHOGENS; EXCISION; RECEPTOR; BACTERIA;

D O I：

10.3390/plants12112147

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Wounds of an acute or chronic etiology affect millions of people worldwide, with increasing prevalence every year. Microbial infections are one of the main causes that impair the wound healing process, and Staphylococcus aureus, a commensal member of the skin microbiota, is one of the main causative agents of wound infections. Crucially, a high proportion of these infections are caused by methicillin-resistant Staphylococcus aureus, which, in addition to beta-lactams, has acquired resistance to almost all the antibacterial agents used to treat it, limiting therapeutic options. Studies on the antimicrobial and healing activities of extracts, essential oils, or metabolites obtained from native plants have been reported in many countries that have a diverse flora and traditions with the use of medicinal plants for the treatment of wound infections. Due to their great chemical diversity, plants have proven to be promising sources of bioactive molecules for the discovery and development of new drugs or strategies for the treatment of wounds. This review highlights the main herbal preparations that have antimicrobial and healing activities with potential for the treatment of wound infections caused by Staphylococcus aureus.

引用

页数：22

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