Predictors of long-term medication adherence in stroke survivors: A multicentre, prospective, longitudinal study

被引：4

作者：

Yoo, Sung-Hee ^{[1
,7
]}

Kim, Gye-Gyoung ^{[1
]}

Kim, Sung Reul ^{[2
]}

Park, Man-Seok ^{[3
]}

Kim, Joon-Tae ^{[3
]}

Choi, Kang-Ho ^{[3
]}

Park, Hyun-Young ^{[4
]}

Yi, Sang-Hak ^{[4
,5
]}

Cha, Jae-Kwan ^{[5
]}

Kim, Dae-Hyun ^{[5
]}

Nah, Hyun-Wook ^{[6
]}

机构：

[1] Chonnam Natl Univ, Coll Nursing, Gwangju, South Korea

[2] Korea Univ, Coll Nursing, Seoul, South Korea

[3] Chonnam Natl Univ Hosp, Med Sch, Dept Neurol, Gwangju, South Korea

[4] Wonkwang Univ Hosp, Dept Neurol, Iksan, South Korea

[5] Dong A Univ Hosp, Dept Neurol, Busan, South Korea

[6] Chungnam Natl Univ, Sejong Hosp, Dept Neurol, Sejong, South Korea

[7] Chonnam Natl Univ, Coll Nursing, 160 Baekseo Ro, Gwangju 61469, South Korea

来源：

JOURNAL OF CLINICAL NURSING | 2023年 / 32卷 / 1-2期

基金：

新加坡国家研究基金会;

关键词：

longitudinal studies; medication adherence; secondary prevention; stroke; TRANSIENT ISCHEMIC ATTACK; SECONDARY PREVENTION; MYOCARDIAL-INFARCTION; ATRIAL-FIBRILLATION; RECURRENT STROKE; RISK; PERSISTENCE; ANTIPLATELET; DISCONTINUATION; ASSOCIATION;

D O I：

10.1111/jocn.16472

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

BackgroundAlthough the optimal use of prescribed medications for stroke survivors is critical for preventing secondary stroke, longitudinal observations of the natural course of medication persistence and adherence in Korean stroke survivors are rare. Furthermore, studies are needed to identify strong predictors influencing medication adherence and to determine whether these predictors change over time. Aims and objectivesTo evaluate the longitudinal medication persistence and adherence at 3 months and 1 year after discharge in all stroke patients and to identify predictors of long-term medication adherence in patients who can self-medicate. DesignA multicentre, prospective, longitudinal descriptive study. MethodsA total of 600 consecutive ischaemic stroke patients were recruited from three stroke centres across Korea, from 1 September, 2017 to 28 February, 2019. Various factors related to medication adherence suggested by the World Health Organisation were investigated through face-to-face interviews at each centre during hospitalisation. Medication persistence and adherence were assessed at 3 months and 1 year after discharge using the eight-item Morisky Medication Adherence Scale through telephone interviews. ResultsOf 537 survivors at 3 months, 526 (98.0%) were persistent and 472 (89.7%) were adherent. Of 493 survivors at 1 year, 477 (96.8%) were persistent and 392 (82.2%) were adherent. Medication belief, income and health literacy were statistically significant predictors of three-month medication adherence, which predicted one-year medication adherence with older age and low income. ConclusionsAmong Korean stroke survivors, three-month and one-year medication persistence and adherence were relatively good. Medication beliefs and three-month medication adherence were important and modifiable factors predicting three-month adherence and one-year adherence, respectively. Relevance to clinical practiceTo increase long-term adherence to medication, various strategies are needed to improve beliefs about medication, taking into account the patient's age and level of knowledge. These interventions need to be initiated during hospitalisation to form early medication habits after discharge.

引用

页码：58 / 70

页数：13

共 55 条

[1] World Medical Association Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects [J].

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 310 (20) :2191-2194

[2] Development and validation of a short-form, rapid estimate of adult literacy in medicine [J].