Leptospiral Uveitis: Case Series and Review of Literature

AimTo present the clinical features and review of literature of leptospiral uveitis.MethodsWe present clinical features of patients with leptospiral uveitis with positive Leptospira IgM antibodies.ResultsTwenty-six eyes of 24 patients, 11 males (45.8%), were included. The mean age was 37.5 +/- 15.6 years. 91.7% had unilateral uveitis, 88.5% panuveitis, 11.5% anterior uveitis, 15.4% had hypopyon, 8% had cataract and 3.8% eyes had cystoid macular edema. Vitritis with characteristic vitreous membranes was an important feature. Retinal and choroidal vasculature were preserved on swept-source optical coherence tomography angiography. Mean presenting BCVA was logMAR0.49 +/- 0.41, while final BCVA was logMAR0.04 +/- 0.13. The mean duration for complete resolution of uveitis was 39.1 +/- 15.5 days. 84.6% eyes achieved BCVA 6/6.ConclusionLeptospiral uveitis is an under-reported entity. It may present as anterior uveitis or panuveitis. It must be included in the differential diagnosis of non-granulomatous uveitis. The visual prognosis is usually favorable even in severe cases.