Investigating the cell permeability of proteolysis-targeting chimeras (PROTACs)

被引：13
|
作者：
Yokoo, Hidetomo [1 ,2 ]
Naito, Mikihiko [1 ,3 ,6 ]
Demizu, Yosuke [1 ,4 ,5 ,7 ]
机构：
[1] Natl Inst Hlth Sci, Div Organ Chem, Kawasaki, Japan
[2] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Med Chem, Kyoto, Japan
[3] Univ Tokyo, Grad Sch Pharmaceut Sci, Lab Targeted Prot Degradat, Tokyo, Japan
[4] Yokohama City Univ, Grad Sch Med Life Sci, Yokohama, Japan
[5] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Div Pharmaceut Sci, Kita, Japan
[6] Univ Tokyo, Grad Sch Pharmaceut Sci, Lab Targeted Prot Degradat, Tokyo 1130033, Japan
[7] Natl Inst Hlth Sci, Div Organ Chem, 3-25-26 Tonomachi, Kawasaki, Kanagawa 2109501, Japan
来源：
EXPERT OPINION ON DRUG DISCOVERY | 2023年 / 18卷 / 04期
基金：
日本学术振兴会;
关键词：
Cell permeability; cell-penetrating peptide; molecular weight; nanoparticle; prodrug; PROTAC; SOLUBILITY; MOLECULES; DESIGN;
D O I：
10.1080/17460441.2023.2187047
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：357 / 361
页数：5
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