Modern Radiotherapy and Cardiac Toxicity in Breast Cancer

被引:0
作者
Iorio, Giuseppe Carlo [1 ]
Chiofalo, Valeria [1 ]
Ricardi, Umberto [1 ]
机构
[1] Univ Torino, Dept Oncol, I-10125 Turin, Italy
关键词
breast cancer; radiotherapy; cardiac toxicity; DIBH; QOL; cardiac sparing; MODULATED RADIATION-THERAPY; BREATHING ADAPTED RADIOTHERAPY; HEART-DISEASE; RESPIRATORY MANEUVERS; 10-YEAR RECURRENCE; PROTON THERAPY; ARC THERAPY; HOLD; MORTALITY; IRRADIATION;
D O I
10.31083/j.ceog5007138
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Radiotherapy (RT) is a mainstay of Breast Cancer (BC) patients therapy. Nonetheless, unintended irradiation of the heart and its sub-structures can result in cardiac toxicity, jeopardizing long-term survivors' quality of life (QOL). Advances in RT delivery techniques deeply impacted this clinical scenario. Indeed, given the non-negligible burden of cardiotoxicity, modern cardiac sparing approaches have a pivotal role. Nonetheless, further evidence is eagerly awaited regarding patients' selection, clinical predictors, biological markers, and particularly heart substructures dose-constraints.
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页数:5
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