Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies

被引：5
作者：
Andrade, Chittaranjan [1 ]
机构：
[1] Natl Inst Mental Hlth & Neurosci, Dept Clin Psychopharmacol & Neurotoxicol, Bangalore, Karnataka, India
来源：
INDIAN JOURNAL OF PSYCHOLOGICAL MEDICINE | 2023年 / 45卷 / 02期
关键词：
Signal; noise; randomized controlled trials; postrandomization bias; observational studies; confounding; regression; RANDOMIZED-TRIALS;
D O I：
10.1177/02537176221149162
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
The previous article in this series explained basic concepts related to statistical signals and statistical noise in research. This article explains statistical noise in the context of randomized controlled trials (RCTs) and observational studies and offers suggestions on how noise in such studies may be reduced so as to better detect and understand the signal. Postrandomization bias related to RCTs and confounding in observational studies are discussed. Examples are provided to facilitate understanding.
引用
收藏
页码：198 / 200
页数：3
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