Hereditary/Familial Ovarian Cancer: Testing Principles and Risk Management

被引：0

作者：

Senter, Leigha ^{[1
]}

机构：

[1] Ohio State Univ, Comprehens Canc Ctr, 2012 Kenny Rd, Columbus, OH 43221 USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2023年 / 21卷 / 5.5期

关键词：

BREAST; BRCA1;

D O I：

10.6004/jnccn.2023.5015

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Although BRCA1 and BRCA2 pathogenic or likely pathogenic variants are a well-established cause of hereditary ovarian cancer, recent studies have brought other homologous recombination repair pathway genes into the limelight. The current NCCN Guidelines reflect the most up-to-date, evidence-based data relating to the risk management of patients who are carriers of BRCA1/2 and/or other variants. Risk-reducing bilateral salpingo-oophorectomy is the current standard of care, but a recommendation for salpingectomy alone may be on the horizon.

引用

页数：3

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