The Association Between Daily Intake of Dietary Supplements and Self-Reported Endometriosis: A NHANES-Based Study

被引:3
作者
Li, Kaiquan [1 ]
Zhang, Wenchao [1 ]
机构
[1] Nanjing Med Univ, Affiliated Hosp 1, Clin Ctr Reprod Med, State Key Lab Reprod Med & Offspring Hlth, Nanjing 210029, Peoples R China
关键词
Dietary fiber; Endometriosis; Fiber density; National Health and Nutrition Examination Survey; Cross-sectional study; FIBER; FAT; PROTEIN; HEALTH;
D O I
10.1007/s43032-024-01464-4
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Dietary supplements are gaining recognition as potential influencers of female reproductive health, but their connection to endometriosis risk remains underexplored. This study addressed this gap, examining the impact of daily dietary supplement intake on the initiation and progression of endometriosis. To explore this, a cross-sectional study was conducted involving 3950 participants representative of the US population from the 1999-2006 National Health and Nutrition Examination Survey (NHANES). Infertility was determined by a question on year-long attempts to become pregnant. Unweighted and weighted multivariate logistic regression analyses assessed the association between dietary supplements and endometriosis risk. Subgroup analysis was conducted based on the participants' body mass index (BMI). The results revealed intriguing patterns. Specifically, higher dietary fiber content (Q4 vs Q1: OR = 0.56, 95% CI = (0.37,0.84), P = 0.0062) and density (Q4 vs Q1: OR = 0.55, 95% CI = (0.38,0.81), P = 0.0035) were linked to reduced risk of endometriosis. Protein content (Q4 vs Q1: OR = 0.47, 95% CI = (0.31,0.74), P = 0.0011) and density (Q4 vs Q1: OR = 0.63, 95% CI = (0.45,0.88), P = 0.0096) similarly exhibited a negative association with endometriosis risk. Interestingly, when stratified by BMI, these effects were pronounced in normal-weight women, whereas they were not evident in the overweight and obese subgroup. Protein content and density showed no significant associations across subpopulations. In conclusion, this study established a negative relationship between dietary fiber and endometriosis, particularly notable in normal-weight women. Future research is essential to validate these findings and establish a causal link between dietary fiber and endometriosis.
引用
收藏
页码:1936 / 1947
页数:12
相关论文
共 50 条
[21]   Association between heart rate and cardiovascular death in patients with coronary heart disease: A NHANES-based cohort study [J].
Ma, Ruicong ;
Gao, Jianbo ;
Mao, Shiyuan ;
Wang, Zhirong .
CLINICAL CARDIOLOGY, 2022, 45 (05) :574-582
[22]   Association between remnant cholesterol (RC) and endometriosis: a cross-sectional study based on NHANES data [J].
Chen, Zeru ;
Li, Ruixuan ;
Guo, Jiajie ;
Ye, Xiaorong ;
Zhou, Yang ;
Cao, Mingzhu .
LIPIDS IN HEALTH AND DISEASE, 2025, 24 (01)
[23]   Association between oxidative balance score and self-reported severe headache or migraine based on NHANES 1999 to 2004 data: A cross-sectional study [J].
Liu, Xinxin ;
Liu, Ran ;
Liu, Wenbin ;
Hua, Rong ;
Xu, Haoyou .
HELIYON, 2024, 10 (06)
[24]   The associations between dietary advanced glycation-end products intake and self-reported infertility in US women: data from the NHANES 2013-2018 [J].
Tong, Lingxia ;
Zhang, Xiaohui ;
Chen, Jingsi ;
He, Huanying ;
Zhang, Wenzhuo ;
Wan, Zhongxiao ;
Zhang, Hong .
SCIENTIFIC REPORTS, 2025, 15 (01)
[25]   Association between adult food insecurity and self-reported asthma in the United States: NHANES 2003-2018 [J].
Ni, Kejie ;
Wan, Yufeng ;
Zheng, Yulong .
JOURNAL OF ASTHMA, 2023, 60 (11) :2074-2082
[26]   Association between dietary selenium intake and endometriosis risk: a cross-sectional analysis [J].
Guo, Jia-Jie ;
Li, Rui-Xuan ;
Shang, Wen-Li ;
Zheng, Ya-Fang ;
Zhu, Guo-Yi ;
Shu, Zhou-Chang ;
Liu, Gui-Chao ;
Ou, Hong-Biao ;
Li, Jia-Ying ;
Guo, Xu-Guang ;
Lin, Li-Hong .
FRONTIERS IN ENDOCRINOLOGY, 2025, 16
[27]   Evaluating the Link Between Self-Reported Endometriosis and Female Sexual Dysfunction [J].
Kling, Juliana M. ;
Ghaith, Summer ;
Smith, Taryn ;
Kapoor, Ekta ;
Wasson, Megan ;
Mara, Kristin ;
Enders, Felicity T. ;
Faubion, Stephanie ;
Kuhle, Carol .
JOURNAL OF SEXUAL MEDICINE, 2022, 19 (10) :1553-1561
[28]   Association between dietary flavonol intake and mortality risk in the US adults from NHANES database [J].
Zong, Zhiqiang ;
Cheng, Xiang ;
Yang, Yang ;
Qiao, Jianchao ;
Hao, Jiqing ;
Li, Fanfan .
SCIENTIFIC REPORTS, 2024, 14 (01)
[29]   Association between dietary magnesium intake and pelvic inflammatory disease in US women: a cross-sectional study of NHANES [J].
Chen, Zeru ;
Wu, Zichun ;
Zhang, Yuying .
FRONTIERS IN NUTRITION, 2024, 11
[30]   The association between dietary vitamin B1 intake and constipation: a population-based study [J].
Du, Wenyi ;
Lu, Lingchen ;
Liu, Yuxuan ;
Yan, Yuxin ;
La, Rui ;
Wu, Qian ;
Xu, Jie ;
Zhou, Xiaojun .
BMC GASTROENTEROLOGY, 2024, 24 (01)