Total Synthesis of the Sesquiterpene (-)-Merrillianin

被引：2

作者：

Shiina, Isamu ^{[1
]}

Iizumi, Takashi ^{[1
]}

Taniguchi, Saori ^{[1
]}

Sugimoto, Masuhiro ^{[1
]}

Shimazaki, Takahisa ^{[1
]}

Yamai, Yu-suke ^{[1
]}

Ogawa, Go ^{[1
]}

Yamada, Tetsuro ^{[1
]}

Shinohara, Shojiro ^{[1
]}

Kageyama, Yosuke ^{[1
]}

Kuboki, Teppei ^{[1
]}

Suwa, Yuki ^{[1
]}

Yonekura, Keita ^{[1
]}

Ito, Keiichi ^{[1
]}

Toyoyama, Kiyotaka ^{[1
]}

Tateyama, Satoru ^{[1
]}

Mori, Takahiro ^{[1
]}

Murata, Takatsugu ^{[1
]}

机构：

[1] Tokyo Univ Sci, Fac Sci, Dept Appl Chem, Tokyo 1628601, Japan

来源：

ORGANIC LETTERS | 2023年 / 26卷 / 16期

关键词：

ALDOL REACTIONS; OLEFINS;

D O I：

10.1021/acs.orglett.3c03877

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first total synthesis of (-)-merrillianin (1), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and seven-membered lactone parts, is demonstrated. This asymmetric total synthesis enabled the absolute stereostructure determination of naturally occurring (-)-1.

引用

页码：3327 / 3331

页数：5

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