Sensing of hyperprolinemia biomarker and its recognition in biological sample through "turn-on" event by Zn-based metal-organic framework

被引：4
作者：
Kanzariya, Dashrathbhai B. [1 ]
Chaudhary, Meetkumar Y. [1 ]
Pal, Tapan K. [1 ,2 ]
机构：
[1] Pandit Deendayal Energy Univ, Dept Chem, Gandhinagar 382426, Gujarat, India
[2] Bajkul Milani Mahavidalaya, Dept Chem, Bajkul 721626, West Bengal, India
来源：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2024年 / 310卷
关键词：
Fluorescent Zn based MOF; Hyperprolinemia biomarker; Colorimetric response; Absorption caused emission; Theoretical investigation; SELECTIVE DETECTION; FABRICATION; SENSOR; IONS;
D O I：
10.1016/j.saa.2024.123882
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
A hydrogen bonded ability metal organic framework (MOF, 1Zn) is used for the ultra -sensitive "turn -on" detection of hyperprolinemia biomarker with ultrafast (within 5 s) colorimetric response making the first MOF based hyperprolinemia biomarker sensor. The detection limit (4.46 ppb) is outperformed compared to all contemporary hyperprolinemia biomarker based sensors. Further, the sensor showed the recognition of biomarker in biological sample (human saliva). The detection of biomarker is also realized through colorimetric response (solution based and paper strip method). The mechanism of sensing is established through the electron transfer and the absorption caused emission (ACE). Moreover, the theoretical study is performed to support the sensing mechanism. The control titration of 1Zn suggest that the free -NH2 group of linker in 1Zn is involved in supramolecular interaction (hydrogen bonding) with the carboxylic group present on biomarker results the facile occurrence of electron transfer and ACE. Consequently, the luminescence "turn -on" effect of 1Zn for hyperprolinemia biomarker is observed.
引用
收藏
页数：5
相关论文
共 40 条
[1]   Amino acid disorders [J].
Aliu, Ermal ;
Kanungo, Shibani ;
Arnold, Georgianne L. .
ANNALS OF TRANSLATIONAL MEDICINE, 2018, 6 (24)
[2]   Plasma co-polymerisation of two strongly interacting monomers: Acrylic acid and allylamine [J].
Beck, AJ ;
Whittle, JD ;
Bullett, NA ;
Eves, P ;
Mac Neil, S ;
McArthur, SL ;
Shard, AG .
PLASMA PROCESSES AND POLYMERS, 2005, 2 (08) :641-649
[3]   Solvothermal Synthesis of High-Performance d10-MOFs with Hydrogel Membranes @ "Turn-On" Monitoring of Formaldehyde in Solution and Vapor Phase [J].
Bej, Sourav ;
Mandal, Sukdeb ;
Mondal, Amita ;
Pal, Tapan K. ;
Banerjee, Priyabrata .
ACS APPLIED MATERIALS & INTERFACES, 2021, 13 (21) :25153-25163
[4]   A human homologue of the Drosophila melanogaster sluggish-A (proline oxidase) gene maps to 22q11.2, and is a candidate gene for type-I hyperprolinaemia [J].
Campbell, HD ;
Webb, GC ;
Young, IG .
HUMAN GENETICS, 1997, 101 (01) :69-74
[5]   Porous Anionic Co(II) Metal-Organic Framework, with a High Density of Amino Groups, as a Superior Luminescent Sensor for Turn-on Al(III) Detection [J].
Chand, Santanu ;
Verma, Gaurav ;
Pal, Arun ;
Pal, Shyam Chand ;
Ma, Shengqian ;
Das, Madhab C. .
CHEMISTRY-A EUROPEAN JOURNAL, 2021, 27 (46) :11804-11810
[6]   Guest-induced conformational switching in a single crystal [J].
Dobrzanska, Liliana ;
Lloyd, Gareth O. ;
Esterhuysen, Catharine ;
Barbour, Leonard J. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (35) :5856-5859
[7]   Turn-on fluorescence detection of specific inorganic anions by Zr(IV)-MOF with amino-functional group [J].
Dong, Jing ;
Wang, Shi-Qing ;
Zhang, Xiao-Yu ;
Huang, Zi-Qing ;
Zhang, Xiu-Du ;
Sun, Wei-Yin .
TUNGSTEN, 2023, 5 (02) :217-224
[8]   Sensing Properties of NH2-MIL-101 Series for Specific Amino Acids via Turn-On Fluorescence [J].
Dong, Jing ;
Dao, Xiao-Yao ;
Zhang, Xiao-Yu ;
Zhang, Xiu-Du ;
Sun, Wei-Yin .
MOLECULES, 2021, 26 (17)
[9]   Amino group dependent sensing properties of metal-organic frameworks: selective turn-on fluorescence detection of lysine and arginine [J].
Dong, Jing ;
Zhang, Xiu-Du ;
Xie, Xia-Fei ;
Guo, Fan ;
Sun, Wei-Yin .
RSC ADVANCES, 2020, 10 (61) :37449-37455
[10]   Photoluminescent metal-organic frameworks and their application for sensing biomolecules [J].
Dong, Jing ;
Zhao, Dan ;
Lu, Yi ;
Sun, Wei-Yin .
JOURNAL OF MATERIALS CHEMISTRY A, 2019, 7 (40) :22744-22767
1234