Serological Evidence for Circulation of Influenza D Virus in the Ovine Population in Italy

被引：1

作者：

Lanave, Gianvito ^{[1
]}

Camero, Michele ^{[1
]}

Coppola, Chiara ^{[2
]}

Marchi, Serena ^{[2
]}

Cascone, Giuseppe ^{[3
]}

Salina, Felice ^{[3
]}

Coltraro, Miriana ^{[3
]}

Odigie, Amienwanlen E. ^{[1
]}

Montomoli, Emanuele ^{[2
,4
]}

Chiapponi, Chiara ^{[5
]}

Cicirelli, Vincenzo ^{[1
]}

Martella, Vito ^{[1
]}

Trombetta, Claudia M. ^{[2
]}

机构：

[1] Univ Aldo Moro Bari, Dept Vet Med, I-70010 Valenzano, Italy

[2] Univ Siena, Dept Mol & Dev Med, I-53100 Siena, Italy

[3] Ist Zooprofilatt Sperimentale Sicilia A Mirri, I-90129 Palermo, Italy

[4] VisMederi Srl, I-53035 Monteriggioni, Italy

[5] Ist Zooprofilatt Sperimentale Lombardia Emilia Rom, OIE Reference Lab Swine Influenza, Sede Terr Parma, I-25124 Brescia, Italy

来源：

PATHOGENS | 2024年 / 13卷 / 02期

基金：

欧盟地平线“2020”;

关键词：

influenza D virus; seroprevalence; hemagglutination inhibition assay; virus neutralization assay; ovine; Italy; PATHOLOGY; LINEAGES;

D O I：

10.3390/pathogens13020162

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Influenza D virus (IDV) is a novel orthomyxovirus initially isolated from pigs exhibiting influenza-like disease in the USA. Since then, IDV has been detected worldwide in several host species, including livestock animals, whilst specific antibodies have been identified in humans, raising concerns about interspecies transmission and zoonotic risks. Few data regarding the seroprevalence of IDV in small ruminants have been available to date. In this study, we assessed the prevalence of antibodies against IDV in ovine serum samples in Sicily, Southern Italy. Six hundred serum samples, collected from dairy sheep herds located in Sicily in 2022, were tested by haemagglutination inhibition (HI) and virus neutralization (VN) assays using reference strains, D/660 and D/OK, representative of two distinct IDV lineages circulating in Italy. Out of 600 tested samples, 168 (28.0%) tested positive to either IDV strain D/660 or D/OK or to both by HI whilst 378 (63.0%) tested positive to either IDV strain D/660 or D/OK or to both by VN. Overall, our findings demonstrate that IDV circulates in ovine dairy herds in Sicily. Since IDV seems to have a broad host range and it has zoonotic potential, it is important to collect epidemiological information on susceptible species.

引用

页数：11

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