Cancer management in terms of precision oncology

被引:0
作者
Mali, Shrikant B. [1 ]
Dahivelkar, Sachinkumar [1 ]
机构
[1] Mahatma Gandhi Vidya Mandirs Dent Coll & Hosp Nash, Nasik, India
关键词
Precision oncology; Cancer; Decision support; Head neck cancer; Clinical trials;
D O I
10.1016/j.oraloncology.2023.106658
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cancer processes have been studied for over a century, but clinical care still relies on morphological and histological approaches. Modern diagnostic and therapy options include molecular characterisation of abnormal genes, cell surface indicators, hormonal/endocrine mediators, and signaling pathways. Targeted medicines, synthetic lethal targeting, and immune checkpoint inhibitors have spurred hope for molecular targets in cancer management. Precision medicine programs aim to transform population-based research into biomarker-driven clinical trials, but disparities in access to genetic profiling and inexpensive precision oncology drugs must be addressed to ensure cost-effective therapies are available to all patients.
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页数:3
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