The impact of ambient air pollution on hospital admissions, length of stay and hospital costs for patients with diabetes mellitus and comorbid respiratory diseases in Panzhihua, Southwest China

被引:6
作者
Li, Xianzhi [1 ,2 ,3 ]
Yu, Bin [4 ]
Li, Yajie [5 ]
Meng, Haorong [6 ]
Shen, Meiying [7 ]
Yang, Yan [1 ,3 ,8 ]
Zhou, Zonglei [9 ]
Liu, Shunjin [1 ,2 ,3 ]
Tian, Yunyun [2 ,3 ]
Yin, Li [2 ,3 ,11 ]
Xing, Xiangyi [1 ,3 ,10 ,11 ]
机构
[1] Panzhihua Cent Hosp, Meteorol Med Res Ctr, Panzhihua, Sichuan, Peoples R China
[2] Panzhihua Cent Hosp, Clin Med Res Ctr, Panzhihua, Sichuan, Peoples R China
[3] Dali Univ, Dali, Yunnan, Peoples R China
[4] Hong Kong Polytech Univ, Sichuan Univ, Inst Disaster Management & Reconstruct, Chengdu, Sichuan, Peoples R China
[5] Tibet Ctr Dis Control & Prevent, Lhasa, Tibet Autonomou, Peoples R China
[6] Yunnan Ctr Dis Control & Prevent, Kunming, Yunnan, Peoples R China
[7] Panzhihua Cent Hosp, Nursing Dept, Panzhihua, Sichuan, Peoples R China
[8] Panzhihua Cent Hosp, Dept Resp & Crit Care Med, Panzhihua, Sichuan, Peoples R China
[9] Fudan Univ, Sch Publ Hlth, Dept Epidemiol, Shanghai, Peoples R China
[10] Panzhihua Cent Hosp, Dept Pharm, Panzhihua, Sichuan, Peoples R China
[11] Panzhihua Cent Hosp, Dept Gastroenterol, 34 Yikang St, Panzhihua 617067, Sichuan, Peoples R China
关键词
CARDIOVASCULAR-DISEASES; PARTICULATE MATTER; HEALTH; MORTALITY; DETERMINANTS; ASSOCIATION; EXPOSURE; RISK;
D O I
10.7189/jogh.13.04118
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
ackground: There is limited evidence on association between air pollutants and hospital admissions, hospital cost and length of stay (LOS) among patients with diabetes mellitus (DM) and comorbid respiratory diseases (RD), especially in low- and middle-income countries (LMICs) with low levels of air pollution.Methods: Daily data on RD-DM patients were collected in Panzhihua from 2016 to 2020. A generalised additive model (GAM) was used to explore the effect of air pollutants on daily hospital admissions, LOS and hospital cost. Attributable risk was employed to estimate RD-DM's burden due to exceeding air pollution exposure, using both 0 microgrammes per cubic metre (mu g/m(3)) and WHO's 2021 air quality guidelines as reference.Results: For each 10 ug/m(3) increase of particles with an aerodynamic diameter <2.5 micron (mu m) (PM2.5), particles with an aerodynamic diameter <10 mu m (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2) and ozone (O-3), the admissions of RD-DM patients increased by 7.25% (95% CI = 4.26 to 10.33), 5.59% (95% CI = 3.79 to 7.42), 10.10% (95% CI = 7.29 to 12.98), 12.33% (95% CI = 8.82 to 15.95) and -2.99% (95% CI = -4.08 to -1.90); per 1 milligramme per cubic metre (mg/m(3)) increase of carbon monoxide (CO) corresponded to a 25.77% (95% CI = 17.88 to 34.19) increment for admissions of RD-DM patients. For LOS and hospital cost, the six air pollutants showed similar effect. Given 0 mu g/m(3) as the reference, NO2 showed the maximum attributable fraction of 32.68% (95% CI = 25.12 to 39.42%), corresponding to an avoidable burden of 5661 (95% CI = 3611 to 5860) patients with RD-DM.Conclusions: There is an association between PM2.5, PM10, SO2, NO2, and CO with increased hospital admissions, LOS and hospital cost in patients with RD-DM. Disease burden of RD-DM may be improved by formulating policies related to air pollutants exposure reduction, especially in LMICs with low levels of air pollution.
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页数:14
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