IgE-mediated Anisakis allergy in children

被引：12

作者：

Pontone, Matteo ^{[1
]}

Giovannini, Mattia ^{[1
,2
,8
]}

Barni, Simona ^{[2
]}

Mori, Francesca ^{[2
]}

Venturini, Elisabetta ^{[3
]}

Galli, Luisa ^{[1
,3
]}

Valleriani, Claudia ^{[1
]}

Vecillas, Leticia De las ^{[4
]}

Sackesen, Cansin ^{[5
]}

Lopata, Andreas Ludwig ^{[6
,7
]}

Buyuktiryaki, Betul ^{[5
]}

机构：

[1] Univ Florence, Dept Hlth Sci, Florence, Italy

[2] Meyer Childrens Hosp, Dept Pediat, Allergy Unit, Florence, Italy

[3] Meyer Childrens Hosp, Infect Dis Unit, Florence, Italy

[4] IdiPAZ, La Paz Univ Hosp, Dept Allergy, Madrid, Spain

[5] Koc Univ, Dept Pediat, Div Pediat Allergy, Sch Med, Istanbul, Turkiye

[6] James Cook Univ, Australian Inst Trop Hlth & Med, Coll Publ Hlth Med & Vet Sci, Mol Allergy Res Lab, Douglas, Qld, Australia

[7] James Cook Univ Singapore, Trop Futures Inst, Singapore, Singapore

[8] Univ Florence, Meyer Childrens Hosp, Dept Pediat, Dept Hlth Sci,Allergy Unit, Viale Pieraccini 24, I-50139 Florence, Italy

来源：

ALLERGOLOGIA ET IMMUNOPATHOLOGIA | 2023年 / 51卷 / 01期

关键词：

Allergen; Anisakis Allergy; Basophil Activation Test; Component-resolved Diagnosis; Fish Parasite; Immunoglobulin E; Infection; Management; Oral Food Challenge; Pediatrics; Skin Prick Test; HEAT-RESISTANT ALLERGEN; MAJOR ALLERGEN; CROSS-REACTIVITY; MOLECULAR-CLONING; BASOPHIL ACTIVATION; CLINICAL-RELEVANCE; CHRONIC URTICARIA; FOOD ALLERGY; S; SIMPLEX;

D O I：

10.15586/aei.v51i1.692

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Anisakids are nematodes responsible for different clinical patterns in humans. The well-known human-infecting Anisakis species include members of the Anisakis simplex (AS) complex. Humans usually contract anisakiasis through ingestion of raw or undercooked seafood con-taining Anisakis larvae. Once Anisakis has been ingested, patients may develop disease driven directly by Anisakis larvae and/or by allergic reaction due to this nematode. The capability of inducing allergic reactions depends on the expression of specific antigens by nematodes and host factors. This study aims to resume actual knowledge about AS and Anisakiasis with regard to epidemiology, pathophysiology, clinical presentation, diagnosis, and treatment. Particular attention is paid to Anisakis allergens and their cross-reactivity on available diagnos-tic methods, and defining a diagnostic pathway for Anisakis allergy. Because only a few data are available in the literature about pediatric population, we focus on this group of patients specifically. (c) 2023 Codon Publications. Published by Codon Publications.

引用

页码：98 / 109

页数：12

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