Electrospray Ionization Ion Mobility Mass Spectrometry

被引：7

作者：

Kohoutek, Katie M. ^{[1
]}

Harrington, Peter de B. ^{[1
]}

机构：

[1] Ohio Univ, Dept Chem & Biochem, 100 Univ Ter, Athens, OH 45701 USA

来源：

CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY | 2023年 / 53卷 / 03期

关键词：

Ion mobility mass spectrometry; applications; DRIFT-TUBE; STRUCTURAL-CHARACTERIZATION; DEGRADATION-PRODUCTS; SAMPLE-INTRODUCTION; METABOLIC ANALYSIS; ORGANIC-COMPOUNDS; MEMBRANE INLET; NEGATIVE-IONS; CRUDE-OIL; DUAL-GATE;

D O I：

10.1080/10408347.2021.1964938

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Electrospray ionization ion mobility mass spectrometry (ESI-IMS-MS) is a rapidly progressing analytical technique for the examination of complex compounds in the gas phase. ESI-IMS-MS separates isomers, provides structural information, and quantitatively identifies peptides, lipids, carbohydrates, polymers, and metabolites in biological samples. ESI-IMS-MS has pharmaceutical, environmental, and manufacturing applications quickly characterizing drugs, petroleum products, and metal macromolecules. This review provides the history of ESI-IMS-MS development and applications to date.

引用

页码：483 / 497

页数：15

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