Electrospray Ionization Ion Mobility Mass Spectrometry

被引:7
作者
Kohoutek, Katie M. [1 ]
Harrington, Peter de B. [1 ]
机构
[1] Ohio Univ, Dept Chem & Biochem, 100 Univ Ter, Athens, OH 45701 USA
关键词
Ion mobility mass spectrometry; applications; DRIFT-TUBE; STRUCTURAL-CHARACTERIZATION; DEGRADATION-PRODUCTS; SAMPLE-INTRODUCTION; METABOLIC ANALYSIS; ORGANIC-COMPOUNDS; MEMBRANE INLET; NEGATIVE-IONS; CRUDE-OIL; DUAL-GATE;
D O I
10.1080/10408347.2021.1964938
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Electrospray ionization ion mobility mass spectrometry (ESI-IMS-MS) is a rapidly progressing analytical technique for the examination of complex compounds in the gas phase. ESI-IMS-MS separates isomers, provides structural information, and quantitatively identifies peptides, lipids, carbohydrates, polymers, and metabolites in biological samples. ESI-IMS-MS has pharmaceutical, environmental, and manufacturing applications quickly characterizing drugs, petroleum products, and metal macromolecules. This review provides the history of ESI-IMS-MS development and applications to date.
引用
收藏
页码:483 / 497
页数:15
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