Venous Thromboembolism in the Inflammatory Rheumatic Diseases

被引:7
作者
Misra, Durga Prasanna [1 ]
Ahmed, Sakir [2 ]
Goyal, Mohit [3 ]
Sharma, Aman
Agarwal, Vikas [1 ]
机构
[1] Sanjay Gandhi Postgrad Inst Med Sci SGPGIMS, Dept Clin Immunol & Rheumatol, C block,Rae Bareli Rd, Lucknow 226014, India
[2] Kalinga Inst Med Sci KIMS, Dept Clin Immunol & Rheumatol, Bhubaneswar 751024, India
[3] CARE Pain & Arthrit Ctr, Dept Rheumatol & Clin Immunol, Udaipur 313002, Rajasthan, India
关键词
Venous thromboembolism; Deep venous thrombosis; Pulmonary embolism; Cardiovascular diseases; Systemic lupus erythematosus; Antiphospholipid antibody syndrome; Rheumatoid arthritis; Vasculitis; SYSTEMIC-LUPUS-ERYTHEMATOSUS; PROTEIN-C RESISTANCE; PULMONARY-EMBOLISM; ANTIPHOSPHOLIPID SYNDROME; INCREASED RISK; ANKYLOSING-SPONDYLITIS; CARDIOVASCULAR-DISEASE; PSORIATIC-ARTHRITIS; BEHCETS-DISEASE; THROMBOSIS;
D O I
10.1016/j.rdc.2022.08.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
VTE risk is increased in most IRDs, based on data from systematic reviews or from individual observational studies. Various factors drive VTE risk in IRDs, particularly a highrisk triple positive APL profile. Duration of anticoagulation following VTE is determined by whether the event was provoked on unprovoked, and whether there exist underlying thrombophilic states such as APLs. VTE associated with BD requires immunosuppression rather than anticoagulation. JAKinibs should be used with caution in those with prior VTE events. Results of ongoing post-marketing surveillance studies of various JAKinibs should help to further clarify VTE risk with this group of medications.
引用
收藏
页码:97 / 127
页数:31
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