Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma

被引:0
作者
Sugihara, Ayano
Ureshino, Hiroshi [1 ]
Yamasaki, Masatora
Fukuda, Makoto
Yoshihara, Maki
Nonaka, Eriko
Miyazaki, Mariko
Fujita, Mai
Ishii, Keitaro
Kamachi, Kazuharu
Sano, Haruhiko
Okamoto, Sho
Itamura, Hidekazu
Yoshimura, Mariko
Katsuya, Hiroo
Ando, Toshihiko
Aoki, Shigehisa
Ubara, Yoshifumi
Kimura, Shinya
机构
[1] Saga Univ, Fac Med, Dept Internal Med, Div Hematol Resp Med & Oncol, Saga, Japan
基金
日本学术振兴会;
关键词
type II cryoglobulinemic vasculitis; membranoproliferative glomerulonephritis; mucosa-associated lymphoid tissue lymphoma; rituximab; bendamustine; B-CELL LYMPHOMA; KIDNEY INVOLVEMENT; SPECTRUM; MYD88;
D O I
10.2169/internalmedicine.0756-22
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 67-year-old man complained of lower limb edema with a purpuric skin rash. Laboratory tests revealed proteinuria, elevated serum creatinine levels, and low serum albumin levels. The patient was also positive for cryoglobulin in serum, immunoglobulin (Ig) M gammopathy, hypocomplementemia, and rheumatoid factor. He was negative for anti-hepatitis C virus antibodies. A pathological analysis of the renal tissue revealed membranoproliferative glomerulonephritis, common histological features of cryoglobulinemic vasculitis (CV), and mucosa-associated lymphoid tissue lymphoma invasion. Although hematologic malignancy is a rare cause of type II CV, these clinical findings suggest that mucosa-associated lymphoid tissue lymphoma (MALT) lymphoma may have been the cause in the present case.
引用
收藏
页码:1983 / 1988
页数:6
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