Preclinical studies targeting CD74 with STRO-001 antibody-drug conjugate in acute leukemia

被引：8

作者：

Le, Quy ^{[1
]}

Tang, Thao ^{[1
]}

Leonti, Amanda ^{[1
]}

Castro, Sommer ^{[1
]}

McKay, Cyd Nourigat ^{[1
]}

Perkins, LaKeisha ^{[1
]}

Pardo, Laura ^{[2
]}

Kirkey, Danielle ^{[1
]}

Hylkema, Tiffany ^{[1
]}

Call, Lindsey ^{[1
]}

Manselle, Makia ^{[1
]}

Abrahams, Cristina ^{[3
]}

Bedard, Kristin ^{[3
]}

Molina, Arturo ^{[3
]}

Brodersen, Lisa Eidenshinck ^{[2
]}

Loken, Michael R. ^{[2
]}

Tarlock, Katherine ^{[1
,5
]}

Meshinchi, Soheil ^{[1
,4
,5
]}

Loeb, Keith R. ^{[1
,6
,7
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Clin Res Div, Seattle, WA USA

[2] Hematologics Inc, Seattle, WA USA

[3] Sutro Biopharma, South San Francisco, CA USA

[4] Univ Washington, Dept Pediat, Seattle, WA USA

[5] Childrens Oncol Grp, Monrovia, CA USA

[6] Univ Washington, Dept Lab Med & Pathol, Seattle, WA USA

[7] Fred Hutch Canc Ctr, 1100 Fairview Ave N, Seattle, WA 98109 USA

来源：

BLOOD ADVANCES | 2023年 / 7卷 / 09期

关键词：

INVARIANT CHAIN; PROLIFERATION; SURVIVAL;

D O I：

10.1182/bloodadvances.2022008303

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1666 / 1670

页数：5

共 12 条

[1] Abrahams Cristina L, 2018, Oncotarget, V9, P37700, DOI 10.18632/oncotarget.26491
[2] CD74 is a member of the regulated intramembrane proteolysis-processed protein family
Becker-Herman, S
Arie, G
Medvedovsky, H
Kerem, A
Shachar, I
[J]. MOLECULAR BIOLOGY OF THE CELL, 2005, 16 (11) : 5061 - 5069
[3] Expression of CD74 by AML blasts and cell lines, and enhanced in vitro cytotoxicity of anti-CD74 antibody after interferon-gamma (IFN-γ) treatment.
Burton, J. D.
Stein, R.
Chandra, A.
Chen, S.
Mishra, N.
Shah, T.
Goldenberg, D. M.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (15)
[4] Chandra AB., 2010, BLOOD, V116, DOI DOI 10.1182/BLOOD.V116.21.2888.2888
[5] Cytokines as regulators of proliferation and survival of healthy and malignant peripheral B cells
Cohen, Sivan
Shachar, Idit
[J]. CYTOKINE, 2012, 60 (01) : 13 - 22
[6] THE SEGMENT OF INVARIANT CHAIN THAT IS CRITICAL FOR ASSOCIATION WITH MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II MOLECULES CONTAINS THE SEQUENCE OF A PEPTIDE ELUTED FROM CLASS-II POLYPEPTIDES
FREISEWINKEL, IM
SCHENCK, K
KOCH, N
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (20) : 9703 - 9706
[7] Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex
Gore, Yael
Starlets, Diana
Maharshak, Nitsan
Becker-Herman, Shirly
Kaneyuki, Utako
Leng, Lin
Bucala, Richard
Shachar, Idit
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (05) : 2784 - 2792
[8] Invariant chain induces B cell maturation by activating a TAFII105-NF-κB-dependent transcription program
Matza, D
Wolstein, O
Dikstein, R
Shachar, I
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (29) : 27203 - 27206
[9] NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report
Ostronoff, Fabiana
Othus, Megan
Gerbing, Robert B.
Loken, Michael R.
Raimondi, Susana C.
Hirsch, Betsy A.
Lange, Beverly J.
Petersdorf, Stephen
Radich, Jerald
Appelbaum, Frederick R.
Gamis, Alan S.
Alonzo, Todd A.
Meshinchi, Soheil
[J]. BLOOD, 2014, 124 (15) : 2400 - 2407
[10] CELL-SURFACE HLA-DR INVARIANT CHAIN COMPLEXES ARE TARGETED TO ENDOSOMES BY RAPID INTERNALIZATION
ROCHE, PA
TELETSKI, CL
STANG, E
BAKKE, O
LONG, EO
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (18) : 8581 - 8585

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