Healthy Vaccinee Bias and MenB-FHbp Vaccine Effectiveness Against Gonorrhea

被引：10

作者：

Abara, Winston E. ^{[1
,5
]}

Bernstein, Kyle T. ^{[1
]}

Lewis, Felicia M. T. ^{[1
]}

Pathela, Preeti ^{[3
]}

Islam, Aras ^{[2
]}

Eberhart, Michael ^{[2
]}

Cheng, Iris ^{[4
]}

Ternier, Alexandra ^{[4
]}

Sanderson Slutsker, Jennifer ^{[3
]}

Madera, Robbie ^{[2
]}

Kirkcaldy, Robert ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Div STD Prevent, Atlanta, GA 30333 USA

[2] Philadelphia Dept Publ Hlth, Philadelphia, PA USA

[3] New York City Dept Hlth & Mental Hyg, Bur STI, New York, NY USA

[4] New York City Dept Hlth & Mental Hyg, Bur Immunizat, New York, NY USA

[5] Ctr Dis Control & Prevent, 1600 Clifton Rd, Atlanta, GA 30333 USA

来源：

SEXUALLY TRANSMITTED DISEASES | 2023年 / 50卷 / 06期

关键词：

NEISSERIA-GONORRHOEAE;

D O I：

10.1097/OLQ.0000000000001793

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Observational studies demonstrated 30% to 40% effectiveness of outer-membrane vesicle (OMV) meningococcal serogroup B vaccines against gonorrhea. To explore whether healthy vaccinee bias influenced such findings, we examined the effectiveness of MenB-FHbp, a non-OMV vaccine that is not protective against gonorrhea. MenB-FHbp was ineffective against gonorrhea. Healthy vaccinee bias likely did not confound earlier studies of OMV vaccines.

引用

页码：E8 / E10

页数：3

共 23 条

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