Nanotechnology: A Promising Approach in Nerve Regeneration

被引:0
作者
Azmi, Namrah [1 ]
Tiwari, Abhishekh [1 ]
Kaur, Navjeet [1 ]
Chaskar, Atul [1 ]
机构
[1] Univ Mumbai, Natl Ctr Nanosci & Nanotechnol, Mumbai 400098, India
关键词
Nerve regeneration; nanomaterials; nanoscaffold; neurogenesis; drug; targeted cells; STEM-CELLS; BIOLOGICAL MACROMOLECULES; CARBON NANOTUBES; IRON-OXIDE; CONDUITS; NANOPARTICLES; NEUROPROTECTION; NANOFIBERS; HYDROGELS; INJURY;
D O I
10.2174/1573413718666220509125522
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
This review focuses on nerve degeneration a major health problem of nowadays, caused due to different nerve diseases or injuries. The low regenerative capacity of the nerve leads to primary brain injury. Clinical therapies available were only able to stabilize lesion progression. Reversal of the degeneration process and functional regeneration promotion were brought about by the implementation of nanotechnology in biology, allowing cell tissue integration. Nanomaterials implemented in the delivery of drugs and bioactive materials treat specifically targeted cells. Nanomaterials made in contact with cells lead to stem cell therapy, promoting stem cell differentiation and neurogenesis. Nanomaterials were also screened for their appropriateness as potential scaffold materials, owing to their neuroprotectant activity in nerve regeneration.
引用
收藏
页码:305 / 321
页数:17
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