Electrospun nanofibres in drug delivery: advances in controlled release strategies

被引：68

作者：

Gaydhane, Mrunalini K. ^{[1
]}

Sharma, Chandra Shekhar ^{[1
]}

Majumdar, Saptarshi ^{[2
]}

机构：

[1] Indian Inst Technol, Dept Chem Engn, Creat & Adv Res Based Nanomat CARBON Lab, Kandi 502285, Telangana, India

[2] Indian Inst Technol, Dept Chem Engn, Polynanobio Lab, Kandi 502285, Telangana, India

来源：

RSC ADVANCES | 2023年 / 13卷 / 11期

关键词：

POLYMER-FREE; CROSS-LINKING; SYSTEMS; NANOPARTICLES; SCAFFOLDS; HYDROGELS; FIBERS; MATS; SKIN; FABRICATION;

D O I：

10.1039/d2ra06023j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Emerging drug-delivery systems demand a controlled or programmable or sustained release of drug molecules to improve therapeutic efficacy and patient compliance. Such systems have been heavily investigated as they offer safe, accurate, and quality treatment for numerous diseases. Amongst newly developed drug-delivery systems, electrospun nanofibres have emerged as promising drug excipients and are coming up as promising biomaterials. The inimitable characteristics of electrospun nanofibres in terms of their high surface-to-volume ratio, high porosity, easy drug encapsulation, and programmable release make them an astounding drug-delivery vehicle.

引用

页码：7312 / 7328

页数：17

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