Analyzing the unperturbed HIV-1 T cell reservoir

被引：3
|
作者：
Lopez, Brianna [1 ]
Siliciano, Robert F. [1 ,2 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD 21218 USA
[2] Howard Hughes Med Inst, Baltimore, MD 21250 USA
来源：
TRENDS IN IMMUNOLOGY | 2023年 / 44卷 / 03期
关键词：
LATENT RESERVOIR;
D O I：
10.1016/j.it.2023.01.007
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The latent reservoir for HIV-1 prevents cure but is difficult to characterize due to the low frequency of latently infected cells and the absence of unique markers. Sun et al. used single cell analysis of T cell surface phenotypes to provide evidence for immune selection of reservoir cells.
引用
收藏
页码：147 / 149
页数：3
相关论文
共 50 条
  • [41] HIV-1 Reservoir Dynamics after Allogeneic Stem Cell Transplantation: Clues to eradicate HIV
    Kwon, M.
    Salgado, M.
    Balsalobre, P.
    Nijhuis, M.
    Blanco, J.
    Miralles, P.
    Serrano, D.
    Gayoso, J.
    Anguita, J.
    Buno, I.
    Wensing, A. M.
    Martinez Picado, J.
    Diez Martin, J. L.
    BONE MARROW TRANSPLANTATION, 2016, 51 : S471 - S472
  • [42] Challenges in HIV-1 Latent Reservoir and Target Cell Quantification in CAR-T Cell and Other Lentiviral Gene Modifying HIV Cure Strategies
    Buck, Amanda M. M.
    Deveau, Tyler-Marie
    Henrich, Timothy J. J.
    Deitchman, Amelia N. N.
    VIRUSES-BASEL, 2023, 15 (05):
  • [43] HIV-1 latent reservoir: size matters
    Hodel, Flavia
    Patxot, Marion
    Snaka, Tiia
    Ciuffi, Angela
    FUTURE VIROLOGY, 2016, 11 (12) : 785 - 794
  • [44] Markers of the HIV-1 reservoir: facts and controversies
    Bruel, Timothee
    Schwartz, Olivier
    CURRENT OPINION IN HIV AND AIDS, 2018, 13 (05) : 383 - 388
  • [45] VIRAL INFECTION Seeding the HIV-1 reservoir
    Nunes-Alves, Claudio
    NATURE REVIEWS MICROBIOLOGY, 2014, 12 (09) : 594 - 595
  • [46] HIV-1 in Monocytes and Macrophages: An Overlooked Reservoir?
    Hassan, Jaythoon
    Browne, Kate
    De Gascun, Cillian
    VIRAL IMMUNOLOGY, 2016, 29 (09) : 532 - 533
  • [47] Is the central nervous system a reservoir of HIV-1?
    Gray, Lachlan R.
    Roche, Michael
    Flynn, Jacqueline K.
    Wesselingh, Steve L.
    Gorry, Paul R.
    Churchill, Melissa J.
    CURRENT OPINION IN HIV AND AIDS, 2014, 9 (06) : 552 - 558
  • [48] HIV-1 Reservoir Association with Immune Activation
    Vallejo, Alejandro
    EBIOMEDICINE, 2015, 2 (09): : 1020 - +
  • [49] The Impact of Cellular Proliferation on the HIV-1 Reservoir
    Virgilio, Maria C.
    Collins, Kathleen L.
    VIRUSES-BASEL, 2020, 12 (02):
  • [50] Urethral macrophages - a new HIV-1 reservoir
    Bradley, Conor A.
    NATURE REVIEWS UROLOGY, 2019, 16 (04) : 205 - 205
12345