Encapsulation of apigenin into β-cyclodextrin metal-organic frameworks with high embedment efficiency and stability

被引：9
作者：
Liu, Yaqi [1 ,2 ]
Yuan, Chao [1 ]
Cui, Bo [1 ]
Zhao, Meng [1 ,2 ]
Yu, Bin [1 ,2 ]
Guo, Li [1 ,2 ]
Liu, Pengfei [1 ,2 ]
Fang, Yishan [1 ,2 ]
机构：
[1] Qilu Univ Technol, Shandong Acad Sci, State Key Lab Biobased Mat & Green Papermaking, Jinan 250353, Peoples R China
[2] Qilu Univ Technol, Shandong Acad Sci, Sch Food Sci & Engn, Jinan 250353, Peoples R China
来源：
FOOD CHEMISTRY | 2024年 / 443卷
基金：
中国国家自然科学基金;
关键词：
beta-Cyclodextrin metal-organic frameworks; Apigenin; Composites; Microstructure; Decomposition kinetic; INCLUSION COMPLEX; DISSOLUTION RATE; SOLUBILITY;
D O I：
10.1016/j.foodchem.2024.138543
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
In an effort to improve the application performance of apigenin, beta-cyclodextrin metal-organic frameworks (BCDMOFs) known as porous materials were used to encapsulate apigenin via an innovative pH-adjusted method. The embedment efficiency had a significant positive pH dependence, reaching a maximum of 79.2 % +/- 1.2 % at pH 12. Scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and thermogravimetric analysis demonstrated formation of apigenin/BCDMOFs composites, and exposure of BCDMOFs pores facilitated high embedment efficiency. Storage stability experiment and kinetic analysis showed degradation of apigenin/BCDMOFs composites was less than that of apigenin alone. Apigenin stability was increased by approximately 18 % after 7 days. BCDMOFs effectively encapsulated and controlled the release of apigenin, and the composites exhibited improved application performance in vitro.
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页数：7
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