Use of Biologics and Stem Cells for Wound Healing in the Horse

被引：3

作者：

Harman, Rebecca M. ^{[1
]}

Rajesh, Aarthi ^{[1
]}

Van de Walle, Gerlinde R. ^{[1
]}

机构：

[1] Cornell Univ, Baker Inst Anim Hlth, Coll Vet Med, Ithaca, NY 14853 USA

来源：

VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE | 2023年 / 39卷 / 03期

基金：

美国食品与农业研究所;

关键词：

Wound healing; Horse; Biologics; Stem cells; Platelet-rich plasma; PLATELET-RICH PLASMA; MESENCHYMAL STROMAL CELLS; DISTAL ASPECT; EQUINE MODEL; MANAGEMENT; REPAIR; GEL; DRESSINGS; AMNION; LIMBS;

D O I：

10.1016/j.cveq.2023.06.003

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Equine clinicians are increasingly interested in using biologics, including cell-based therapies, to treat cutaneous wounds of horses. In vitro studies have shown that MSCs secrete factors that promote wound healing and that primary keratinocytes can be reprogrammed to be used for transplantation. Small in vivo experiments suggest that biologic dressings and dressing products, stem cells, and PRP may pro-mote skin wound healing. Delivery methods should be optimized, and larger trials are needed to confirm whether biologics do indeed improve skin wound healing in horses.

引用

页码：525 / 539

页数：15

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