Atypical myelin oligodendrocyte glycoprotein antibody-associated optic neuritis and acute demyelinating polyneuropathy after SARS-CoV-2 infection: Case report and literature review

被引：12

作者：

Bosello, Francesca ^{[1
,5
]}

Marastoni, Damiano ^{[2
]}

Pizzini, Francesca Benedetta ^{[3
,4
]}

Zaffalon, Chiara ^{[1
]}

Zuliani, Andrea ^{[1
]}

Turri, Giulia ^{[2
]}

Mariotto, Sara ^{[2
]}

Bonacci, Erika ^{[1
]}

Pedrotti, Emilio ^{[1
]}

Calabrese, Massimiliano ^{[2
]}

机构：

[1] AOUI Univ Verona, Dept Neurosci Biomed & Movement Sci, Ocular Immunol & Neuroophthalmol Serv, Eye Clin, Verona, Italy

[2] Univ Verona, Dept Neurosci Biomed & Movement Sci, Neurol Sect, Verona, Italy

[3] Integrated Univ Hosp Verona, Dept Diagnost & Pathol, Neuroradiol Unit, Verona, Italy

[4] Integrated Univ Hosp Verona, Dept Diagnost & Pathol, Radiol Unit, Verona, Italy

[5] Ple Alberto Scuro 1, I-37135 Verona, Italy

来源：

JOURNAL OF NEUROIMMUNOLOGY | 2023年 / 375卷

关键词：

Optic neuritis; Myelin oligodendrocyte glycoprotein; MOG IgG; Sars-Cov-2; Acute inflammatory demyelinating; polyneuropathy;

D O I：

10.1016/j.jneuroim.2022.578011

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Post-infectious immune-mediated neurological complications of Sars-Cov-2 have been increasingly recognized since the novel pandemic emerged. We describe the case of a 74 years-old patient who developed a Myelin Oligodendrocyte Glycoprotein (MOG) antibody-associated unilateral retrobulbar optic neuritis a few weeks after paucisymptomatic COVID-19 disease and, subsequently, after the resolution of the optic neuritis, an acute in-flammatory demyelinating polyneuropathy. So far, no cases of these two neurological manifestations have been reported in the same patient. We herein report a case characterized by both manifestations and review the accumulating literature regarding MOG antibody-associated disease following SarsCov-2 infection.

引用

页数：5

共 24 条

[1]

Assavapongpaiboon Buravej, 2022, Am J Ophthalmol Case Rep, V26, P101491, DOI 10.1016/j.ajoc.2022.101491

[2] Clinical phenotype, radiological features, and treatment of myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) optic neuritis [J].