Novel Bioengineered Collagen with Manuka Honey and Hydroxyapatite Sheet for the Treatment of Lower Extremity Chronic Wounds in an Urban Hospital Wound Care Setting

Introduction. A novel BCMH sheet has been shown to achieve improved wound closure rates in chronic and acute wounds when compared with SOC. Objective. This retrospective evaluation assessed chronic wound closure rates with SOC or treatment with the BCMH sheet in an urban hospital wound clinic. Methods. Forty-seven chronic wounds were treated with either SOC or the BCMH sheet. The primary endpoint was time to closure. For wounds that did not close, investigations were conducted to determine the reason. Results. Twenty wounds were treated with SOC, which varied in usage of multiple products and/or therapies, and 27 wounds were treated with the BCMH sheet. The average initial wound size was not statistically different between the groups. In both groups, most wounds that were treated did not close. For wounds that did close, the average time to closure was two times faster in the BCMH group compared with the SOC group (7.4 weeks and 14.8 weeks, respectively; P < .05). Conclusions. This retrospective evaluation showed average time to wound closure to be significantly faster with BCMH compared with SOC in patients who maintained adherence with regular visits.