Acute Kidney Injury and Hepatorenal Syndrome in Patients with Cirrhosis

被引：4

作者：

Ozturk, Nazli Begum ^{[1
]}

Dinc, Ece Janet ^{[2
]}

Swami, Abhishek ^{[3
]}

Gurakar, Ahmet ^{[4
]}

机构：

[1] Beaumont Hosp, Dept Internal Med, Royal Oak, MI 48073 USA

[2] Baskent Univ, Sch Med, TR-06790 Ankara, Turkiye

[3] Beaumont Hosp, Div Nephrol, Royal Oak, MI 48073 USA

[4] Johns Hopkins Univ Hosp, Div Gastroenterol & Hepatol, Baltimore, MD 21287 USA

来源：

JOURNAL OF CLINICAL MEDICINE | 2024年 / 13卷 / 01期

关键词：

cirrhosis; hepatorenal syndrome; terlipressin; acute kidney injury; liver disease; GELATINASE-ASSOCIATED LIPOCALIN; TERLIPRESSIN PLUS ALBUMIN; CHRONIC LIVER-FAILURE; DIFFERENTIAL-DIAGNOSIS; BIOMARKERS; DISEASE; PATHOPHYSIOLOGY; PREDICTORS; CREATININE; MANAGEMENT;

D O I：

10.3390/jcm13010199

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acute kidney injury (AKI) is common in hospitalized patients with cirrhosis. Hepatorenal syndrome (HRS) is a type of AKI known as HRS-AKI. It is a severe complication of cirrhosis with high morbidity and mortality. While certain vasoconstrictor medications have been shown to improve HRS-AKI, no clear transplant-free survival benefit has been reported with medical therapies. Patients with HRS-AKI should be considered for urgent liver transplantation evaluation. In this review, we discuss the most recent updates on the definition, diagnosis, and management of AKI in cirrhosis, with special a emphasis on HRS.

引用

页数：14

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