Loss of effectiveness with an implanted drug delivery system for intrathecal pain therapy due to corrosion
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作者:
Reining, Marco
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机构:
Dept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
SRH Wald Klinikum Gera GmbH, Dept Pain Med & Palliat Care, Str Friedens 122, D-07549 Gera, GermanyDept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
Reining, Marco
[1
,3
]
Kretzschmar, Michael
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机构:
Dept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
SRH Univ Appl Hlth Sci, Gera, GermanyDept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
Kretzschmar, Michael
[1
,2
]
机构:
[1] Dept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
[2] SRH Univ Appl Hlth Sci, Gera, Germany
[3] SRH Wald Klinikum Gera GmbH, Dept Pain Med & Palliat Care, Str Friedens 122, D-07549 Gera, Germany
IntroductionIntrathecal drug delivery is an established invasive treatment option. Most common complication is catheter malfunction, which can lead to overdose or withdrawal. Case PresentationA 61-year-old female patient underwent an elective replacement of an intrathecal drug delivery pump. The patient complained about a loss of effectiveness over the past 2 years. Intraoperatively, a white mass corresponding to morphine precipitation in the pump pocket was found, which appeared to be due to corrosion at the pump-catheter connection site. ConclusionsRecommendations on how to deal with the decreasing effectiveness of intrathecal drug delivery and on intraoperative catheter handling are provided.
机构:
Case Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
Mayo Clin, Dept Anesthesiol & Perioperat Med, Rochester, MN USACase Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
Ade, Timothy
Roh, Justin
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Case Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
Hosp Univ Penn, Dept Anesthesiol & Crit Care, 3400 Spruce St, Philadelphia, PA 19104 USACase Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
Roh, Justin
Sharma, Gautam
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Case Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Cleveland, OH 44106 USACase Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
Sharma, Gautam
Mohan, Mahesh
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机构:
Case Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
Mercy One Med Ctr, Waterloo, IA USACase Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
Mohan, Mahesh
DeLozier, Sarah J.
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机构:
Univ Hosp Cleveland Med Ctr, Clin Res Ctr, Cleveland, OH USACase Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
DeLozier, Sarah J.
Janes, Jessica L.
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机构:
Univ Hosp Cleveland Med Ctr, Clin Res Ctr, Cleveland, OH USACase Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
Janes, Jessica L.
Hayek, Salim M.
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Case Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USACase Western Reserve Univ, Univ Hosp Cleveland Med Ctr, Dept Anesthesiol, Div Pain Med, Cleveland, OH 44106 USA
机构:
Univ Utah, Dept Anesthesiol, 30 N 1900 E,Room C344, Salt Lake City, UT 84132 USA
Huntsman Canc Inst, Salt Lake City, UT USAUniv Utah, Dept Anesthesiol, 30 N 1900 E,Room C344, Salt Lake City, UT 84132 USA
Sindt, Jill E.
Larsen, Steven D.
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Univ Utah, Dept Anesthesiol, 30 N 1900 E,Room C344, Salt Lake City, UT 84132 USAUniv Utah, Dept Anesthesiol, 30 N 1900 E,Room C344, Salt Lake City, UT 84132 USA
Larsen, Steven D.
Dalley, Andrew P.
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Univ Utah, Sch Med, Salt Lake City, UT USAUniv Utah, Dept Anesthesiol, 30 N 1900 E,Room C344, Salt Lake City, UT 84132 USA
Dalley, Andrew P.
Collier, Willem H.
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机构:
Univ Utah, Dept Populat Hlth Sci, Salt Lake City, UT USAUniv Utah, Dept Anesthesiol, 30 N 1900 E,Room C344, Salt Lake City, UT 84132 USA
Collier, Willem H.
Brogan, Shane E.
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Univ Utah, Dept Anesthesiol, 30 N 1900 E,Room C344, Salt Lake City, UT 84132 USA
Huntsman Canc Inst, Salt Lake City, UT USAUniv Utah, Dept Anesthesiol, 30 N 1900 E,Room C344, Salt Lake City, UT 84132 USA
机构:
Princess Margaret Hosp, Dept Anesthesiol, Subiaco, WA, AustraliaPrincess Margaret Hosp, Dept Anesthesiol, Subiaco, WA, Australia
Johnson, Marlene L.
Visser, Eric J.
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机构:
Fremantle Hosp, Pain Med Unit, Fremantle, WA, AustraliaPrincess Margaret Hosp, Dept Anesthesiol, Subiaco, WA, Australia
Visser, Eric J.
Goucke, C. Roger
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机构:
Univ Western Australia, Sch Med & Pharmacol, Nedlands, WA 6009, Australia
Sir Charles Gairdner Hosp, Dept Pain Management, Perth, WA, AustraliaPrincess Margaret Hosp, Dept Anesthesiol, Subiaco, WA, Australia