Loss of effectiveness with an implanted drug delivery system for intrathecal pain therapy due to corrosion
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作者:
Reining, Marco
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Dept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
SRH Wald Klinikum Gera GmbH, Dept Pain Med & Palliat Care, Str Friedens 122, D-07549 Gera, GermanyDept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
Reining, Marco
[1
,3
]
Kretzschmar, Michael
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Dept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
SRH Univ Appl Hlth Sci, Gera, GermanyDept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
Kretzschmar, Michael
[1
,2
]
机构:
[1] Dept Pain Med & Palliat Care, SRH Wald Klinikum Gera GmbH, Gera, Germany
[2] SRH Univ Appl Hlth Sci, Gera, Germany
[3] SRH Wald Klinikum Gera GmbH, Dept Pain Med & Palliat Care, Str Friedens 122, D-07549 Gera, Germany
IntroductionIntrathecal drug delivery is an established invasive treatment option. Most common complication is catheter malfunction, which can lead to overdose or withdrawal. Case PresentationA 61-year-old female patient underwent an elective replacement of an intrathecal drug delivery pump. The patient complained about a loss of effectiveness over the past 2 years. Intraoperatively, a white mass corresponding to morphine precipitation in the pump pocket was found, which appeared to be due to corrosion at the pump-catheter connection site. ConclusionsRecommendations on how to deal with the decreasing effectiveness of intrathecal drug delivery and on intraoperative catheter handling are provided.
机构:
Mayo Clin, Div Pain Med, Dept Anesthesiol & Perioperat Med, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Div Pain Med, Dept Anesthesiol & Perioperat Med, 200 First St SW, Rochester, MN 55905 USA
Wanderman, Robalee L.
Hagedorn, Jonathan M.
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Mayo Clin, Div Pain Med, Dept Anesthesiol & Perioperat Med, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Div Pain Med, Dept Anesthesiol & Perioperat Med, 200 First St SW, Rochester, MN 55905 USA
机构:
Konkuk Univ Hosp, Dept Anesthesiol & Pain Med, Seoul, South KoreaSeoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South Korea
Kim, Jae Hun
Nahm, Francis Sangun
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Seoul Natl Univ, Dept Anesthesiol & Pain Med, Bundang Hosp, Songnam, South KoreaSeoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South Korea
Nahm, Francis Sangun
Chang, Jee Eun
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Seoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South KoreaSeoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South Korea
Chang, Jee Eun
Park, Soo Young
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Seoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South KoreaSeoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South Korea
Park, Soo Young
Kim, Yong Chul
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Seoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South KoreaSeoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South Korea
Kim, Yong Chul
Lee, Sang Chul
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Seoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South KoreaSeoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Seoul 110744, South Korea
机构:
Harvard Med Sch, Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USAHarvard Med Sch, Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
Hao, David
Lee, Donghwan
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Harvard Med Sch, Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USAHarvard Med Sch, Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
Lee, Donghwan
Shah, Shivam S.
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Louisiana State Univ, Sch Med, Hlth Sci Ctr Shreveport, Shreveport, LA 71103 USAHarvard Med Sch, Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
Shah, Shivam S.
Shekoohi, Sahar
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Louisiana State Univ, Dept Anesthesiol, Hlth Sci Ctr Shreveport, Shreveport, LA 71103 USAHarvard Med Sch, Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
Shekoohi, Sahar
Kaye, Alan D.
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Louisiana State Univ, Dept Anesthesiol, Hlth Sci Ctr Shreveport, Shreveport, LA 71103 USA
Louisiana State Univ, Hlth Sci Ctr Shreveport, Dept Pharmacol Toxicol & Neurosci, Shreveport, LA 71103 USAHarvard Med Sch, Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
机构:
Al Jahra Hosp, Minist Hlth, Dept Anaesthesiol Crit Care & Pain Management, Salmiya, State Of Kuwait, KuwaitAl Jahra Hosp, Minist Hlth, Dept Anaesthesiol Crit Care & Pain Management, Salmiya, State Of Kuwait, Kuwait
Upadhyay, Surjya Prasad
Mallick, Piyush N.
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Al Jahra Hosp, Minist Hlth, Dept Anaesthesia Crit Care & Pain Management, Salmiya, State Of Kuwait, KuwaitAl Jahra Hosp, Minist Hlth, Dept Anaesthesiol Crit Care & Pain Management, Salmiya, State Of Kuwait, Kuwait
机构:
Brigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USABrigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA
Xing, Fangfang
Yong, R. Jason
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Brigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USABrigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA
Yong, R. Jason
Kaye, Alan David
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机构:
Louisiana State Univ, Hlth Sci Ctr, Dept Anesthesiol, New Orleans, LA USABrigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA
Kaye, Alan David
Urman, Richard D.
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Brigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USABrigham & Womens Hosp, Dept Anesthesiol Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA