Analysis of Kojic Acid-Rich AcOET Extract (KaRE) from the Endophytic Fungus Aspergillus sp., Isolated from Hancornia speciosa and Determination of its Nitric Oxide (NO) Activity

被引：1

作者：

Santos, Mario F. C. ^{[1
]}

Costa, Edvaldo S. ^{[2
]}

Matos, Humberto ^{[3
]}

Morais-Urano, Raquel P. ^{[4
]}

Silva, Geraldo H. ^{[5
]}

机构：

[1] Univ Fed Espirito Santo, Ctr Ciencias Exatas Nat & Saude, Dept Fis & Quim, Alto Univ S-N, BR-29500000 Alegre, ES, Brazil

[2] Univ Fed Sergipe, Dept Letras Libras, BR-49100000 Sao Cristovao, SE, Brazil

[3] Univ Fed Sergipe, Dept Fisiol, BR-49100000 Sao Cristovao, SE, Brazil

[4] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13566590 Sao Carlos, SP, Brazil

[5] Univ Fed Vicosa, Inst Ciencias Exatas, BR-38810000 Rio Parnaiba, MG, Brazil

来源：

REVISTA VIRTUAL DE QUIMICA | 2023年 / 15卷 / 03期

关键词：

Aspergillus sp; kojic acid; Nitric Oxide (NO); scavenging activity; HPLC-UV; ANTIOXIDANT; NITRATE;

D O I：

10.21577/1984-6835.20220108

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Kojic acid is produced by different types of fungi such as Apergillus sp. It has great potential for industrial application, being found in the cosmetic and health industries. The fungus Aspergillus sp. isolated from the leaves of Hancornia speciosa was grown in liquid medium PDB yielding kojic acid-rich ethyl acetate extract. Analysis of H-1 and C-13 NMR of the ethyl acetate extract showed the metabolite kojic acid as the main compound, and it was quantified by HPLC-UV. The kojic acid-rich ethyl acetate extract exhibited potent Nitric Oxide (NO) scavenging activity in vitro (antioxidant activity), showing the biotechnologic potential of fungus Aspergillus sp.

引用

页码：446 / 451

页数：6