Significance of Diabetic Kidney Disease Biomarkers in Predicting Metabolic-Associated Fatty Liver Disease

被引:3
作者
Bae, Jaehyun [1 ]
Lee, Byung-Wan [2 ]
机构
[1] Catholic Kwandong Univ, Int St Marys Hosp, Dept Internal Med, Div Endocrinol & Metab,Coll Med, Int St, Incheon 22711, South Korea
[2] Yonsei Univ, Dept Internal Med, Div Endocrinol & Metab, Coll Med, Seoul 03722, South Korea
关键词
diabetic kidney disease; metabolic-associated fatty liver disease; biomarker; GELATINASE-ASSOCIATED LIPOCALIN; ACID-BINDING PROTEIN; SERUM CYSTATIN C; INSULIN-RESISTANCE; PROXIMAL TUBULE; THERAPEUTIC TARGETS; RENAL DYSFUNCTION; MOLECULE-1; KIM-1; URINARY ENZYMES; FETUIN-A;
D O I
10.3390/biomedicines11071928
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Metabolic-associated fatty liver disease (MAFLD) and diabetic kidney disease (DKD) share various pathophysiological factors, and epidemiological evidence suggests that these two diseases are associated. Albuminuria and the estimated glomerular filtration rate, which are conventional biomarkers of DKD, are reportedly associated with the risk or severity of MAFLD. Recently, novel DKD biomarkers reflecting renal tubular injury have been introduced to complement conventional DKD markers. In this article, we looked at previous studies that showed an association between MAFLD and DKD, and also reviewed the significance of DKD biomarkers as predictive risk factors for MAFLD.
引用
收藏
页数:13
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