Adult Attention-Deficit/Hyperactivity Disorder: a Narrative Review of Biological Mechanisms, Treatments, and Outcomes

被引：13
作者：
Pagan, Antonio F. [1 ]
Huizar, Yazmine P. [1 ]
Short, Tucker R. [1 ]
Gotcher, Zoe [1 ]
Schmidt, Adam T. [1 ]
机构：
[1] Texas Tech Univ, Dept Psychol Sci, Psychol Sci Bldg,2700 18th St, Lubbock, TX 79410 USA
来源：
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS | 2023年 / 23卷 / 08期
关键词：
ADHD; Adult; Neurodevelopmental disorders; Treatment; Assessment; Neuropsychology; DEFICIT HYPERACTIVITY DISORDER; DIFFERENTIAL-DIAGNOSIS; COLLEGE-STUDENTS; ADHD; MEDICATION; CHILDREN; METAANALYSIS; TRAJECTORIES; NEUROBIOLOGY; PARTICIPANTS;
D O I：
10.1007/s11910-023-01280-4
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Purpose of ReviewAttention-deficit/hyperactivity disorder (ADHD) is a heterogeneous and complex neurodevelopmental disorder related to disruptions in various neuronal structures and pathways, dopamine (DA) transporter, and receptor genes, resulting in cognitive and regulation deficits. This article reviews recent research on the biological mechanisms and markers, clinical manifestations, treatments, and outcomes of adult ADHD as well as current controversies within the field.Recent FindingsNew research identifies white matter disruptions in multiple cortical pathways in adults with ADHD. New treatments for ADHD in adults such as viloxazine ER have shown preliminary effectiveness in addition to research showing transcranial direct current stimulation can be an effective treatment for adults with ADHD.Although questions exist about the effectiveness of current assessments of and treatments for adult ADHD, recent findings represent a step towards improving the quality of life and outcomes for individuals experiencing this life-long, chronic health condition.
引用
收藏
页码：451 / 460
页数：10
相关论文
共 50 条
[31]   Update on Attention-Deficit/Hyperactivity Disorder and Tic Disorders: A Review of the Current Literature [J].
Simpson, Heather A. ;
Jung, Leah ;
Murphy, Tanya K. .
CURRENT PSYCHIATRY REPORTS, 2011, 13 (05) :351-356
[32]   Methylphenidate for attention-deficit/hyperactivity disorder in adults: a narrative review [J].
Rafał R. Jaeschke ;
Ewelina Sujkowska ;
Magdalena Sowa-Kućma .
Psychopharmacology, 2021, 238 :2667-2691
[33]   Nonpharmacologic Treatments for Attention-Deficit/Hyperactivity Disorder: A Systematic Review [J].
Goode, Adam P. ;
Coeytaux, Remy R. ;
Maslow, Gary R. ;
Davis, Naomi ;
Hill, Sherika ;
Namdari, Behrouz ;
LaPointe, Nancy M. Allen ;
Befus, Deanna ;
Lallinger, Kathryn R. ;
Bowen, Samantha E. ;
Kosinski, Andrzej ;
McBroom, Amanda J. ;
Sanders, Gillian D. ;
Kemper, Alex R. .
PEDIATRICS, 2018, 141 (06)
[34]   Pharmacogenetics of response to methylphenidate in adult patients with Attention-Deficit/Hyperactivity Disorder (ADHD): A systematic review [J].
Contini, Veronica ;
Rovaris, Diego L. ;
Victor, Marcelo M. ;
Grevet, Eugenio H. ;
Rohde, Luis A. ;
Bau, Claiton H. D. .
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2013, 23 (06) :555-560
[35]   The comorbidity of adult attention-deficit/hyperactivity disorder in bipolar disorder patients [J].
Karaahmet, Elif ;
Konuk, Numan ;
Dalkilic, Alican ;
Saracli, Ozge ;
Atasoy, Nuray ;
Kurcer, Mehmet A. ;
Atik, Levent .
COMPREHENSIVE PSYCHIATRY, 2013, 54 (05) :549-555
[36]   Gaze-based attention refocusing training in virtual reality for adult attention-deficit/hyperactivity disorder [J].
Selaskowski, Benjamin ;
Asche, Laura Marie ;
Wiebe, Annika ;
Kannen, Kyra ;
Aslan, Behrem ;
Gerding, Thiago Morano ;
Sanchez, Dario ;
Ettinger, Ulrich ;
Koelle, Markus ;
Lux, Silke ;
Philipsen, Alexandra ;
Braun, Niclas .
BMC PSYCHIATRY, 2023, 23 (01)
[37]   Antidepressants in the treatment of adult attention-deficit hyperactivity disorder: a systematic review [J].
Wim Verbeeck ;
Siegfried Tuinier ;
Geertruida E. Bekkering .
Advances in Therapy, 2009, 26 :170-184
[38]   On Criteria Diversity in Diagnostics of Adult Attention-Deficit/Hyperactivity Disorder [J].
Wandschneider, R. ;
Marx, I. .
FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE, 2016, 84 :S71-S73
[39]   Managing Adult Attention-Deficit/Hyperactivity Disorder: To Treat or Not To Treat? [J].
Deshpande, Swapna ;
Ostermeyer, Britta ;
Lokhande, Akshay ;
Abid, Humaira ;
Shah, Asim A. .
PSYCHIATRIC ANNALS, 2017, 47 (06) :315-321
[40]   Cerebellar network alterations in adult attention-deficit/hyperactivity disorder [J].
Parkkinen, Salla ;
Radua, Joaquim ;
Andrews, Derek S. ;
Murphy, Declan ;
Dell'Acqua, Flavio ;
Parlatini, Valeria .
JOURNAL OF PSYCHIATRY & NEUROSCIENCE, 2024, 49 (04) :E233-E241
12345