Preparation of Novel Electrospun Organic-Inorganic Hybrid Nanofibers Based on Polycaprolactone, Glycine Betaine, and Calcium Carbonate (P/G/CaCO3-EPnF)

被引:1
作者
Butto-Miranda, Nicole [1 ,2 ]
Cabrera-Barjas, Gustavo [3 ]
Ibanez, Andres [4 ]
Neira-Carrillo, Andronico [2 ,5 ]
机构
[1] Univ Chile, Programa Doctorado Ciencias Silvoagropecuarias & V, Campus Sur,Santa Rosa 11315, Santiago 8820808, Chile
[2] Univ Chile, Dept Biol & Anim Sci, Santa Rosa 11735, Santiago 8820808, Chile
[3] Univ Concepcion, Unidad Desarrollo Tecnol UDT, Ave Cordillera 3624,Parque Ind Coronel, Concepcion 4191996, Chile
[4] Univ Chile, Fac Ciencias Fis & Matemat, Dept Fis, Santiago 8370456, Chile
[5] Adv Ctr Chron Dis ACCDIS, Santiago, Chile
关键词
polycaprolactone; calcium carbonate; electrospinning; hybrid materials; organic-inorganic nanofibers; glycine betaine; COMPOSITE; CONSTRUCTION; MORPHOLOGY; CRYSTAL; GROWTH; CACO3;
D O I
10.3390/cryst13040611
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
Biomedicine requires materials able to respond to specific needs without affecting the organism. Organic-inorganic fibrillar polymeric matrices possess unique properties that may fulfill these needs. In the present study, different topology-controlled poly(epsilon-caprolactone)-based fibrillar matrices containing glycine betaine at varying concentrations (0.5, 1, and 2% w/v) were prepared via electrospinning. The matrices were used as substrates in calcium carbonate crystallization assays with gas diffusion to obtain a single organic-inorganic hybrid material. The resulting matrices and crystalline material were characterized using spectroscopic, microscopic, and thermogravimetric analyses. The incorporation of glycine betaine into a poly(epsilon-caprolactone) mesh modified the diameter of the fibers, without affecting the thermal behavior of the matrices. However, the chemical and morphological characteristics of the matrices did influence in vitro inorganic mineralization. The thermogravimetric analysis of the matrices, performed after the mineralization tests, demonstrated the existence of a new organic-inorganic hybrid material with unique properties, which is discussed in the present study.
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页数:18
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