Ir-Catalyzed Transfer Hydrogenation and Alkylation of Aldehydes and Ketones Using Ethanol as the Hydrogen Source

被引：2
|
作者：
Yadav, Suman [1 ]
Rao Kuram, Malleswara [1 ,2 ]
机构：
[1] Cent Drug Res Inst, Med & Proc Chem Div, CSIR, Lucknow 226031, India
[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2023年
关键词：
alkylation; ethanol; ketones; reduction; transfer hydrogenation; ASYMMETRIC TRANSFER HYDROGENATION; ALPHA-ALKYLATION; CONJUGATE REDUCTION; PRIMARY ALCOHOLS; N-ALKYLATION; LIGANDS; METHANOL; COMPLEX; MILD; ALKYNES;
D O I：
10.1002/ejoc.202201344
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Bio-derived ethanol is a promising green and sustainable hydrogen-donor solvent. Herein, we have developed Ir-catalyzed transfer hydrogenation of ketones and aldehydes using ethanol as a hydrogen source with amides as simple ligands. Furthermore, the alkylation of ketones and tandem alkylation/transfer hydrogenation of acetophenones is reported with ethanol.
引用
收藏
页数：6
相关论文
共 50 条
  • [41] Asymmetric Ir-catalyzed hydrogenation of 1,5-benzodiazepinones using mixtures of ligands
    Lyubimov, S. E.
    Ozolin, D. V.
    Davankov, V. A.
    RUSSIAN CHEMICAL BULLETIN, 2017, 66 (06) : 1059 - 1061
  • [42] Room-temperature Ru(II)-catalyzed transfer hydrogenation of ketones and aldehydes in air
    Zhao, Miao
    Yu, Zhengkun
    Yan, Shenggang
    Li, Yang
    TETRAHEDRON LETTERS, 2009, 50 (32) : 4624 - 4628
  • [43] EFFICIENT RHODIUM-CATALYZED HYDROGENATION OF ALDEHYDES AND KETONES
    BURK, MJ
    HARPER, TGP
    LEE, JR
    KALBERG, C
    TETRAHEDRON LETTERS, 1994, 35 (28) : 4963 - 4966
  • [44] Palladium-catalyzed transfer hydrogenation of terminal alkynes using ethanol as the hydrogen donor
    Hui, Jie
    Wang, Feng
    JOURNAL OF CHEMICAL RESEARCH, 2022, 46 (06)
  • [45] Enantioselective Ir-Catalyzed Allylic Alkylation of Racemic Allylic Alcohols with Malonates
    Meng, Chun-Yan
    Liang, Xiao
    Wei, Kun
    Yang, Yu-Rong
    ORGANIC LETTERS, 2019, 21 (03) : 840 - 843
  • [46] Transfer hydrogenation of ketones and aldehydes using simple aluminum catalysts.
    Campbell, EJ
    Zhou, HY
    Nguyen, ST
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 222 : U619 - U619
  • [47] Methanol as Hydrogen Source: Transfer Hydrogenation of Aldehydes near Room Temperature
    Chen, Zhenyu
    Chen, Guanhong
    Aboo, Ahmed H.
    Iggo, Jonathan
    Xiao, Jianliang
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2020, 9 (08) : 1174 - 1178
  • [48] Reductive alkylation of proteins using iridium catalyzed transfer hydrogenation
    McFarland, JM
    Francis, MB
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (39) : 13490 - 13491
  • [49] A new chiral sulfinyl-NH-pyridine ligand for Ir-catalyzed asymmetric transfer hydrogenation reaction
    Tang, Lei
    Wang, Qiwei
    Wang, Juanjuan
    Lin, Zechao
    Wang, Xiaobei
    Cun, Linfeng
    Yuan, Weicheng
    Zhu, Jin
    Liao, Jian
    Deng, Jingen
    TETRAHEDRON LETTERS, 2012, 53 (30) : 3839 - 3842
  • [50] Methanol as hydrogen source: Chemoselective transfer hydrogenation of α,β-unsaturated ketones with a rhodacycle
    Aboo, Ahmed H.
    Begum, Robina
    Zhao, Liangliang
    Farooqi, Zahoor H.
    Xiao, Jianhang
    CHINESE JOURNAL OF CATALYSIS, 2019, 40 (11) : 1795 - 1799
12345