Ir-Catalyzed Transfer Hydrogenation and Alkylation of Aldehydes and Ketones Using Ethanol as the Hydrogen Source

被引：2

作者：

Yadav, Suman ^{[1
]}

Rao Kuram, Malleswara ^{[1
,2
]}

机构：

[1] Cent Drug Res Inst, Med & Proc Chem Div, CSIR, Lucknow 226031, India

[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2023年

关键词：

alkylation; ethanol; ketones; reduction; transfer hydrogenation; ASYMMETRIC TRANSFER HYDROGENATION; ALPHA-ALKYLATION; CONJUGATE REDUCTION; PRIMARY ALCOHOLS; N-ALKYLATION; LIGANDS; METHANOL; COMPLEX; MILD; ALKYNES;

D O I：

10.1002/ejoc.202201344

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bio-derived ethanol is a promising green and sustainable hydrogen-donor solvent. Herein, we have developed Ir-catalyzed transfer hydrogenation of ketones and aldehydes using ethanol as a hydrogen source with amides as simple ligands. Furthermore, the alkylation of ketones and tandem alkylation/transfer hydrogenation of acetophenones is reported with ethanol.

引用

页数：6

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