Ir-Catalyzed Transfer Hydrogenation and Alkylation of Aldehydes and Ketones Using Ethanol as the Hydrogen Source

被引：2
|
作者：
Yadav, Suman [1 ]
Rao Kuram, Malleswara [1 ,2 ]
机构：
[1] Cent Drug Res Inst, Med & Proc Chem Div, CSIR, Lucknow 226031, India
[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2023年
关键词：
alkylation; ethanol; ketones; reduction; transfer hydrogenation; ASYMMETRIC TRANSFER HYDROGENATION; ALPHA-ALKYLATION; CONJUGATE REDUCTION; PRIMARY ALCOHOLS; N-ALKYLATION; LIGANDS; METHANOL; COMPLEX; MILD; ALKYNES;
D O I：
10.1002/ejoc.202201344
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Bio-derived ethanol is a promising green and sustainable hydrogen-donor solvent. Herein, we have developed Ir-catalyzed transfer hydrogenation of ketones and aldehydes using ethanol as a hydrogen source with amides as simple ligands. Furthermore, the alkylation of ketones and tandem alkylation/transfer hydrogenation of acetophenones is reported with ethanol.
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页数：6
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