Strong host phylogenetic and ecological effects on host competency for avian influenza in Australian wild birds

被引：17

作者：

Wille, Michelle ^{[1
,2
,3
,4
]}

Lisovski, Simeon ^{[5
]}

Roshier, David ^{[5
]}

Ferenczi, Marta ^{[5
]}

Hoye, Bethany J. J. ^{[5
]}

Leen, Trent ^{[6
,7
]}

Warner, Simone ^{[8
]}

Fouchier, Ron A. M. ^{[9
]}

Hurt, Aeron C. C. ^{[3
]}

Holmes, Edward C. C. ^{[1
,2
]}

Klaassen, Marcel ^{[5
,10
]}

机构：

[1] Univ Sydney, Sydney Inst Infect Dis, Sch Life & Environm Sci, Sydney, NSW 2006, Australia

[2] Univ Sydney, Sch Med Sci, Sydney, NSW 2006, Australia

[3] Peter Doherty Inst Infect & Immun, WHO Collaborating Ctr Reference & Res Influenza, Melbourne, Vic 3000, Australia

[4] Univ Melbourne, Peter Doherty Inst Infect & Immun, Dept Microbiol & Immunol, Melbourne, Vic 3000, Australia

[5] Deakin Univ, Ctr Integrat Ecol, Geelong, Vic 3217, Australia

[6] Geelong Field & Game, Geelong, Vic 3340, Australia

[7] Field & Game Australia, Wetlands Environm Taskforce, Seymour, Vic 3660, Australia

[8] AgriBio Ctr AgriBiosci, Agr Victoria Res, Bundoora, Vic 3083, Australia

[9] Erasmus MC, Dept Virosci, NL-3015 GE Rotterdam, Netherlands

[10] Australasian Wader Studies Grp, Thornbury, ACT 2605, Australia

来源：

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 2023年 / 290卷 / 1991期

基金：

澳大利亚研究理事会;

关键词：

avian influenza; influenza A virus; host range; host susceptibility; host-pathogen dynamics; phylogenetic effects; NORTHERN AUSTRALIA; R PACKAGE; A VIRUS; SURVEILLANCE; CHARADRIIFORMES; PREVALENCE; INFECTION; WATERFOWL; PATTERNS; DRIVERS;

D O I：

10.1098/rspb.2022.2237

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Host susceptibility to parasites is mediated by intrinsic and external factors such as genetics, ecology, age and season. While waterfowl are considered central to the reservoir community for low pathogenic avian influenza A viruses (LPAIV), the role of host phylogeny has received limited formal attention. Herein, we analysed 12 339 oropharyngeal and cloacal swabs and 10 826 serum samples collected over 11 years from wild birds in Australia. As well as describing age and species-level differences in prevalence and seroprevalence, we reveal that host phylogeny is a key driver in host range. Seasonality effects appear less pronounced than in the Northern Hemisphere, while annual variations are potentially linked to El Nino-Southern Oscillation. Our study provides a uniquely detailed insight into the evolutionary ecology of LPAIV in its avian reservoir community, defining distinctive processes on the continent of Australia and expanding our understanding of LPAIV globally.

引用

页数：9