Post hoc analysis of CheckMate 274 trial for programmed death-ligand 1 expression and outcome

被引：0

作者：

Bhirud, Deepak Prakash ^{[1
]}

机构：

[1] AIIMS, Dept Urol, Jodhpur, Rajasthan, India

来源：

INDIAN JOURNAL OF UROLOGY | 2023年 / 39卷 / 04期

关键词：

D O I：

10.4103/iju.iju_172_23

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The CheckMate 274 trial was a phase 3, multicentric, double.blind, randomized trial published in 2021.[1] The trial included patients with muscle invasive bladder cancer who were at high risk of recurrence following radical cystectomy and reported a superior disease.free survival (DFS) with adjuvant nivolumab. In both the intention to treat analysis and in patients with tumor programmed death.ligand 1 (PD.L1) positivity of more than 1%, the trial reported a superior DFS when nivolumab was prescribed in the adjuvant setting as compared to the placebo. © 2023 Indian Journal of Urology.

引用

页码：335 / 336

页数：2

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