An assessment of co-contraction in reinnervated muscle

被引：1

作者：

Wilcox, Matthew ^{[1
,2
,3
]}

Brown, Hazel ^{[1
,2
]}

Johnson, Kathryn ^{[1
]}

Sinisi, Marco ^{[1
]}

Quick, Tom J. ^{[1
,2
]}

机构：

[1] Royal Natl Orthopaed Hosp, Peripheral Nerve Injury Res Unit, London HA7 4LP, England

[2] UCL, Ctr Nerve Engn, London WC1E 6BT, England

[3] UCL, Sch Pharm, Dept Pharmacol, London WC1N 1AX, England

来源：

REGENERATIVE MEDICINE | 2024年 / 19卷 / 04期

关键词：

co-contraction; MRC grading; muscle fatigue; muscle reinnervation; nerve transfer; peripheral nerve injury; NERVE TRANSFER; BRACHIAL-PLEXUS; ANTAGONIST MUSCLES; ELBOW FLEXOR; ULNAR NERVE; MOVEMENT; COACTIVATION; SYNAPSES; RECOVERY; FATIGUE;

D O I：

10.2217/rme-2023-0049

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Aim: To investigate co-contraction in reinnervated elbow flexor muscles following a nerve transfer. Materials & methods: 12 brachial plexus injury patients who received a nerve transfer to reanimate elbow flexion were included in this study. Surface electromyography (EMG) recordings were used to quantify co-contraction during sustained and repeated isometric contractions of reinnervated and contralateral uninjured elbow flexor muscles. Reuslts: For the first time, this study reveals reinnervated muscles demonstrated a trend toward higher co-contraction ratios when compared with uninjured muscle and this is correlated with an earlier onset of muscle fatigability. Conclusion: Measurements of co-contraction should be considered within muscular function assessments to help drive improvements in motor recovery therapies.

引用

页码：161 / 170

页数：10

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