The cost of inflammatory bowel disease in high-income settings: a Lancet Gastroenterology & Hepatology Commission

被引：103

作者：

Burisch, Johan ^{[1
,2
]}

Zhao, Mirabella ^{[1
,2
]}

Odes, Selwyn ^{[3
]}

De Cruz, Peter ^{[6
,7
]}

Vermeire, Severine ^{[8
,9
]}

Bernstein, Charles N. ^{[10
,11
]}

Kaplan, Gilaad G. ^{[12
]}

Duricova, Dana ^{[13
,14
]}

Greenberg, Dan ^{[4
,5
]}

Melberg, Hans O. ^{[15
,16
]}

Watanabe, Mamoru ^{[17
]}

Ahn, Hyeong Sik ^{[18
]}

Targownik, Laura ^{[19
]}

Pittet, Valerie E. H. ^{[20
]}

Annese, Vito ^{[21
]}

Park, K. T. ^{[22
,23
]}

Katsanos, Konstantinos H. ^{[24
]}

Hoivik, Marte L. ^{[16
,25
]}

Krznaric, Zeljko ^{[26
]}

Chaparro, Maria ^{[27
,28
]}

Loftus, Edward V., Jr. ^{[29
]}

Lakatos, Peter L. ^{[30
,31
]}

Gisbert, Javier P. ^{[27
,28
]}

Bemelman, Willem ^{[32
]}

Moum, Bjorn ^{[25
]}

Gearry, Richard B. ^{[33
]}

Kappelman, Michael D. ^{[34
,35
]}

Hart, Ailsa ^{[36
]}

Pierik, Marieke J. ^{[37
]}

Andrews, Jane M. ^{[38
,39
]}

Ng, Siew C. ^{[40
]}

D'Inca, Renata ^{[41
]}

Munkholm, Pia ^{[42
]}

机构：

[1] Copenhagen Univ Hosp Amager & Hvidovre, Gastro Unit, Div Med, Hvidovre, Denmark

[2] Copenhagen Univ Hosp Amager & Hvidovre, Copenhagen Ctr Inflammatory Bowel Dis Children Ad, Hvidovre, Denmark

[3] Ben Gurion Univ Negev, Fac Hlth Sci, Beer Sheva, Israel

[4] Ben Gurion Univ Negev, Sch Publ Hlth, Fac Hlth Sci, Dept Hlth Policy & Management, Beer Sheva, Israel

[5] Ben Gurion Univ Negev, Guilford Glazer Fac Business & Management, Beer Sheva, Israel

[6] Austin Hlth, Dept Gastroenterol, Melbourne, Vic, Australia

[7] Univ Melbourne, Austin Acad Ctr, Dept Med, Melbourne, Vic, Australia

[8] Univ Hosp Leuven, Dept Gastroenterol & Hepatol, Leuven, Belgium

[9] Katholieke Univ Leuven, Fac Med, Leuven, Belgium

[10] Univ Manitoba, IBD Clin & Res Ctr, Max Rady Coll Med, Rady Fac Hlth Sci, Winnipeg, MB, Canada

[11] Univ Manitoba, Dept Internal Med, Max Rady Coll Med, Rady Fac Hlth Sci, Winnipeg, MB, Canada

[12] Univ Calgary, Dept Med & Community Hlth Sci, Calgary, AB, Canada

[13] ISCARE, IBD Clin & Res Ctr IBD, Prague, Czech Republic

[14] Charles Univ Prague, Dept Pharmacol, Fac Med, Prague, Czech Republic

[15] Arctic Univ Norway, Univ Tromso, Dept Community Med, Tromso, Norway

[16] Oslo Univ Hosp, Dept Gastroenterol, Oslo, Norway

[17] Tokyo Med & Dent Univ, Adv Res Inst, Tokyo, Japan

[18] Korea Univ, Dept Prevent Med, Coll Med, Seoul, South Korea

[19] Univ Toronto, Mt Sinai Hosp, Div Gastroenterol & Hepatol, Dept Med, Toronto, ON, Canada

[20] Univ Lausanne, Dept Epidemiol & Hlth Syst, Ctr Primary Care & Publ Hlth, Lausanne, Switzerland

[21] Fakeeh Univ Hosp, Div Gastroenterol, Dept Internal Med, Dubai, U Arab Emirates

[22] Packard Hlth Alliance, Stanford Hlth Care, Alameda, CA USA

[23] Genentech Inc, Roche Grp, San Francisco, CA USA

[24] Univ Ioannina, Div Gastroenterol, Sch Hlth Sci, Fac Med,Dept Internal Med, Ioannina, Greece

[25] Univ Oslo, Inst Clin Med, Oslo, Norway

[26] Univ Hosp Zagreb, Dept Gastroenterol Hepatol & Nutr, Zagreb, Croatia

[27] Univ Autonoma Madrid, Hosp Univ Princesa, Inst Invest Sanitaria Princesa, Madrid, Spain

[28] Ctr Invest Biomed Red Enfermedades Hepat & Digest, Madrid, Spain

[29] Mayo Clin, Div Gastroenterol & Hepatol, Coll Med & Sci, Rochester, MN USA

[30] McGill Univ, Div Gastroenterol, Montreal, PQ, Canada

[31] Semmelweis Univ, Dept Internal Med & Oncol, Budapest, Hungary

[32] Univ Amsterdam, Dept Surg, Med Ctr, Amsterdam, Netherlands

[33] Univ Otago, Dept Med, Christchurch, New Zealand

[34] Univ N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC USA

[35] Univ N Carolina, Ctr Gastrointestinal Biol & Dis, Chapel Hill, NC USA

[36] St Marks Hosp, Harrow, Middx, England

[37] Maastricht Univ, Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Maastricht, Netherlands

[38] Royal Adelaide Hosp, Dept Gastroenterol & Hepatol, IBD Serv, Adelaide, SA, Australia

[39] Univ Adelaide, Fac Hlth Sci, Adelaide, SA, Australia

[40] Chinese Univ Hong Kong, Dept Med & Therapeut, Li Ka Shing Inst Hlth Sci, State Key Lab Digest Dis,Inst Digest Dis, Hong Kong, Peoples R China

[41] Univ Padua, Dept Surg Oncol & Gastroenterol Sci, Padua, Italy

[42] Copenhagen Univ Hosp North Zealand, Dept Gastroenterol, Hillerod, Denmark

来源：

LANCET GASTROENTEROLOGY & HEPATOLOGY | 2023年 / 8卷 / 05期

关键词：

QUALITY-OF-CARE; REPORTED OUTCOME MEASURES; CROHNS-DISEASE; HEALTH-CARE; ULCERATIVE-COLITIS; ANTI-TNF; RISK-FACTORS; INDIVIDUALIZED THERAPY; DOSE INTENSIFICATION; COMBINATION THERAPY;

D O I：

10.1016/S2468-1253(23)00003-1

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The cost of caring for patients with inflammatory bowel disease (IBD) continues to increase worldwide. The cause is not only a steady increase in the prevalence of Crohn's disease and ulcerative colitis in both developed and newly industrialised countries, but also the chronic nature of the diseases, the need for long-term, often expensive treatments, the use of more intensive disease monitoring strategies, and the effect of the diseases on economic productivity. This Commission draws together a wide range of expertise to discuss the current costs of IBD care, the drivers of increasing costs, and how to deliver affordable care for IBD in the future. The key conclusions are that (1) increases in health-care costs must be evaluated against improved disease management and reductions in indirect costs, and (2) that overarching systems for data interoperability, registries, and big data approaches must be established for continuous assessment of effectiveness, costs, and the cost-effectiveness of care. International collaborations should be sought out to evaluate novel models of care (eg, value-based health care, including integrated health care, and participatory health-care models), as well as to improve the education and training of clinicians, patients, and policy makers.

引用

页码：458 / 492

页数：35

共 242 条

[21] Characteristics of High-Need, High-Cost Patients: A "Best-Fit" Framework Synthesis [J].