Hydrogel-based dressings designed to facilitate wound healing

被引:20
|
作者
Zhang, Wei [1 ]
Liu, Lulu [2 ]
Cheng, Hui [1 ]
Zhu, Jing [2 ]
Li, Xinyi [1 ]
Ye, Sheng [2 ]
Li, Xiaojing [1 ]
机构
[1] Anhui Med Univ, Affiliated Hosp 1, Dept Plast Surg, Hefei 230022, Anhui, Peoples R China
[2] Anhui Agr Univ, Sch Mat & Chem, Hefei 230036, Anhui, Peoples R China
来源
MATERIALS ADVANCES | 2024年 / 5卷 / 04期
基金
中国国家自然科学基金;
关键词
CHITOSAN-BASED HYDROGELS; NECROSIS-FACTOR-ALPHA; SUPRAMOLECULAR HYDROGEL; MACROPHAGE POLARIZATION; INJECTABLE HYDROGELS; TISSUE ADHESIVES; TREATING WOUNDS; HYALURONIC-ACID; GROWTH-FACTOR; ANTIBACTERIAL;
D O I
10.1039/d3ma00682d
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The escalating prevalence of wounds, particularly chronic wounds, poses significant challenges in terms of treatment management and has led to an increase in healthcare expenditure. Hydrogel-based dressings play a crucial role in wound management due to their unique properties. However, there remains a lack of comprehensive reviews on the use of hydrogel-based dressings for wound healing. This review commences with an overview of the process and characteristics of wound healing. Furthermore, we summarize the various functions of hydrogel-based dressings in promoting wound healing, including adhesive property, antibacterial efficacy, hemostasis, angiogenesis promotion, anti-oxidation, anti-inflammatory effect, self-healing, and conductivity. We further discuss the challenges encountered during the healing of different types of wounds, particularly diabetic wounds, and outline the latest advancements in the application of hydrogel-based dressings in the management of different types of wounds. In addition, we conclude and provide an outlook on the application of hydrogel-based dressings in wound healing, with the aim of further enhancing their ability to promote wound healing. This review provides an overview of the functionalities of hydrogel-based dressings and their role in promoting wound healing.
引用
收藏
页码:1364 / 1394
页数:31
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