Clinical Outcomes With Momelotinib vs Ruxolitinib in Patients With Myelofibrosis and Anemia: Subgroup Analysis of SIMPLIFY-1

被引：0
|
作者：
Gupta, Vikas [1 ]
Oh, Stephen [2 ]
Devos, Timothy [3 ,4 ]
Dubruille, Viviane [5 ]
Catalano, John [6 ,7 ]
Somervaille, Timothy [8 ,9 ]
Giraldo, Pilar [10 ,11 ]
Kosugi, Hiroshi [12 ]
Sacha, Tomasz [13 ]
Mayer, Jiri [14 ]
Illes, Arpad [15 ]
Ellis, Catherine [16 ]
Wang, Zhaohui [16 ]
Kawashima, Jun [17 ]
Mesa, Ruben [18 ]
机构：
[1] Princess Margaret Canc Ctr, Toronto, ON, Canada
[2] Washington Univ, Sch Med, St Louis, MO 14263 USA
[3] Univ Hosp Leuven, Leuven, Belgium
[4] Katholieke Univ Leuven, Leuven, Belgium
[5] CHU Nantes, Nantes, France
[6] Monash Univ, Frankston, Australia
[7] Frankston Hosp, Frankston, Australia
[8] Christie NHS Fdn Trust, Manchester, Lancs, England
[9] Canc Res UK Manchester Inst, Manchester, Lancs, England
[10] Miguel Servet Univ Hosp, Zaragoza, Spain
[11] Ctr Invest Biomed Red Enfermadades Raras, Zaragoza, Spain
[12] Ogaki Municipal Hosp, Ogaki, Japan
[13] Jagiellonian Univ Hosp, Krakow, Poland
[14] Univ Hosp Brno, Brno, Czech Republic
[15] Univ Debrecen, Dept Internal Med, Div Haematol, Fac Med, Debrecen, Hungary
[16] GSK Plc, Philadelphia, PA USA
[17] Sierra Oncol, San Mateo, CA USA
[18] Wake Forest Univ, Sch Med, Winston Salem, NC USA
来源：
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA | 2023年 / 23卷
关键词：
MPN; myelofibrosis; momelotinib; anemia; hemoglobin;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
MPN-551
引用
收藏
页码：S402 / S403
页数：2
相关论文
共 31 条
  • [21] A subgroup analysis of JUMP, a phase IIIb, expanded-access study evaluating the safety and efficacy of ruxolitinib in patients with myelofibrosis in a Brazilian cohort
    Tavares, Renato
    Souza, Carmino Antonio De
    Paley, Carole
    Bouard, Catherine
    Tiwar, Ranjan
    Pasquini, Ricardo
    HEMATOLOGY TRANSFUSION AND CELL THERAPY, 2020, 42 (01) : 46 - 53
  • [22] Clinical Benefit of Pelabresib (Cpi-0610) in Combination with Ruxolitinib in JAK Inhibitor Treatment-Naive Myelofibrosis Patients: Interim Efficacy Subgroup Analysis from Arm 3 of the MANIFEST Phase 2 Study
    Gupta, Vikas
    Kremyanskaya, Marina
    Mascarenhas, John
    Palandri, Francesca
    Patriarca, Andrea
    Devos, Timothy
    Harrison, Claire
    Passamonti, Francesco
    Rampal, Raajit
    Mead, Adam
    Scandura, Joseph
    Hobbs, Gabriela
    Talpaz, Moshe
    Granacher, Nikki
    Somervaille, Tim
    Hoffman, Ronald
    Bose, Prithviraj
    Colak, Gozde
    Shao, James
    Cui, Jike
    Bobba, Suresh
    Luptakova, Katarina
    Verstovsek, Srdan
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2021, 21 : S362 - S362
  • [23] Dosing and clinical outcomes of ruxolitinib in patients with myelofibrosis in a real-world setting: Interim results of the Italian observational study (ROMEI)
    Breccia, Massimo
    Palandri, Francesca
    Martelli, Maurizio
    Mendicino, Francesco
    Malato, Alessandra
    Palumbo, Giuseppe A.
    Sibilla, Silvia
    Di Renzo, Nicola
    Abruzzese, Elisabetta
    Siragusa, Sergio
    Crugnola, Monica
    Selleri, Carmine
    Pane, Fabrizio
    Sportoletti, Paolo
    Martino, Bruno
    Impera, Stefana
    Ricco, Alessandra
    Langella, Maria
    Ditonno, Paolo
    Carli, Giuseppe
    Itri, Federico
    Liberati, Anna Marina
    Urbano, Tiziana
    Tafuri, Agostino
    Polizzi, Vita
    Pastore, Domenico
    Morsia, Erika
    Benevolo, Giulia
    Micucci, Giorgia
    Farina, Gabriella
    Bonifacio, Massimiliano
    Elli, Elena Maria
    Gardellini, Angelo
    De Stefano, Valerio
    Caocci, Giovanni
    Falcone, Antonietta Pia
    Vallisa, Daniele
    Brociner, Marco
    Tiribelli, Mario
    Binotto, Gianni
    Pocali, Barbara
    Cavazzini, Francesco
    Tomassetti, Simona
    Lunghi, Francesca
    Di Ianni, Mauro
    Allegra, Alessandro
    Anaclerio, Barbara
    Mazzotta, Serena
    Orofino, Nicola
    Gherlinzoni, Filippo
    CANCER, 2025, 131 (07)
  • [24] Efficacy and Safety of Add-on Parsaclisib to Ruxolitinib Therapy in Myelofibrosis Patients With Low Versus Higher Baseline Platelet Counts: A Subgroup Analysis of Data From a Phase 2 Study
    Yacoub, Abdulraheem
    Borate, Uma
    Rampal, Raajit
    Ali, Haris
    Wang, Eunice
    Gerds, Aaron
    Hobbs, Gabriela
    Kremyanskaya, Marina
    Winton, Elliott
    O'Connell, Casey
    Goel, Swati
    Oh, Stephen
    Schiller, Gary
    Assad, Albert
    Erickson-Viitanen, Sue
    Zhou, Feng
    Daver, Naval
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2022, 22 : S324 - S324
  • [25] The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis
    Verstovsek, Srdan
    Mesa, Ruben A.
    Gotlib, Jason
    Levy, Richard S.
    Gupta, Vikas
    DiPersio, John F.
    Catalano, John V.
    Deininger, Michael
    Miller, Carole
    Silver, Richard T.
    Talpaz, Moshe
    Winton, Elliott F.
    Harvey, Jimmie H., Jr.
    Arcasoy, Murat O.
    Hexner, Elizabeth
    Lyons, Roger M.
    Paquette, Ronald
    Raza, Azra
    Vaddi, Kris
    Erickson-Viitanen, Susan
    Sun, William
    Sandor, Victor
    Kantarjian, Hagop M.
    BRITISH JOURNAL OF HAEMATOLOGY, 2013, 161 (04) : 508 - 516
  • [26] Impact of anemia on clinical outcomes in patients with acute heart failure: A systematic review and meta-analysis
    Pan, Jiahui
    Liu, Meijun
    Huang, Jiamin
    Chen, Liuying
    Xu, Yizhou
    CLINICAL CARDIOLOGY, 2024, 47 (02)
  • [27] Impact of Anemia on Clinical Outcomes in Atrial Fibrillation Patients on Oral Anticoagulants: A Prognostic Meta-Analysis
    Amin, Ahmed Mazen
    Elbenawi, Hossam
    Odat, Ramez M.
    Elgebaly, Mohamed
    Al-shammari, Ali Saad
    Manasrah, Almothana
    Nakhla, Michael
    Ayman, Dina
    Ali, Mohamed Ahmed
    Helmi, Ahmed
    Abuelazm, Mohamed
    Ternes, Caique M. P.
    Abdelazeem, Basel
    Zeb, Irfan
    Deshmukh, Abhishek J.
    Desimone, Christopher V.
    d'Avila, Andre
    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2025, 36 (02) : 430 - 448
  • [28] Preoperative Anemia and Low Hemoglobin Level Are Associated With Worse Clinical Outcomes in Patients With Bladder Cancer Undergoing Radical Cystectomy: A Meta-Analysis
    Xia, Leilei
    Guzzo, Thomas J.
    CLINICAL GENITOURINARY CANCER, 2017, 15 (02) : 263 - 272
  • [29] Characteristics and Clinical Outcomes in Patients With Polycythemia Vera Receiving Ruxolitinib After Hydroxyurea: A Longitudinal Analysis From the Prospective Observational Study of Patients With Polycythemia Vera in US Clinical Practices Trial (REVEAL)
    Gerds, Aaron T.
    Grunwald, Michael R.
    Oh, Stephen T.
    Braunstein, Evan
    Xue, Zhenyi
    Bhat, Valkal
    Yu, Jingbo
    Mesa, Ruben
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2023, 23 : S404 - S405
  • [30] Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea
    Alvarez-Larran, Alberto
    Garrote, Marta
    Ferrer-Marin, Francisca
    Perez-Encinas, Manuel
    Mata-Vazquez, M. Isabel
    Bellosillo, Beatriz
    Arellano-Rodrigo, Eduardo
    Gomez, Montse
    Garcia, Regina
    Garcia-Gutierrez, Valentin
    Gasior, Mercedes
    Cuevas, Beatriz
    Angona, Anna
    Gomez-Casares, Maria Teresa
    Martinez, Clara M.
    Magro, Elena
    Ayala, Rosa
    del Orbe-Barreto, Rafael
    Perez-Lopez, Raul
    Fox, Maria Laura
    Raya, Jose-Maria
    Guerrero, Lucia
    Garcia-Hernandez, Carmen
    Caballero, Gonzalo
    Murillo, Ilda
    Xicoy, Blanca
    Ramirez, M. Jose
    Carreno-Tarragona, Gonzalo
    Hernandez-Boluda, Juan Carlos
    Pereira, Arturo
    CANCER, 2022, 128 (13) : 2441 - 2448
1234