Locally Advanced Adenoid Cystic Carcinoma of the Breast-A Case Report with a Review of the Literature

被引：4

作者：

Rypel, Joanna ^{[1
]}

Kubacka, Paulina ^{[1
]}

Mykala-Ciesla, Joanna ^{[1
]}

Pajak, Jacek ^{[2
]}

Bulska-Bedkowska, Weronika ^{[1
]}

Chudek, Jerzy ^{[1
]}

机构：

[1] Med Univ Silesia, Dept Internal Med & Oncol Chemotherapy, PL-40055 Katowice, Poland

[2] Med Univ Silesia, Dept Pathomorphol, PL-40055 Katowice, Poland

来源：

MEDICINA-LITHUANIA | 2023年 / 59卷 / 11期

关键词：

triple-negative breast cancer; adenoid cystic carcinoma; metastasis; systemic therapy; METASTASIS; MUTATIONS;

D O I：

10.3390/medicina59112005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Breast cancer (BC) is a heterogeneous disease distinguished by four main subtypes based on the expression of estrogen, progesterone receptors, and human epidermal growth factor-2 on the cancer cells. Triple-negative breast cancer (TNBC) consists of approximately 10-20% of all BCs and is characterized by a poor prognosis. Adenoid cystic carcinoma (ACC) of the breast is a rare, special type of TNBC with low metastatic potential and usually favorable prognosis. There are no established recommendations concerning systemic therapy in advanced ACC. We present a case of a 70-year-old woman with locally advanced ACC with progression after radical mastectomy, and review the literature concerning the treatment of metastatic disease focused on systemic therapy.

引用

页数：12

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