Somatic mutations, genome mosaicism and aging

被引:0
作者
Lodato, Michael A. [1 ]
Vijg, Jan [2 ,3 ]
机构
[1] Univ Massachusetts, Chan Med Sch, Dept Mol Cell & Canc Biol, Worcester, MA 01002 USA
[2] Shanghai Jiao Tong Univ, Sch Publ Hlth, Sch Med, Ctr Single Cell Om, Shanghai, Peoples R China
[3] Albert Einstein Coll Med, Dept Genet, New York, NY 10461 USA
来源
FRONTIERS IN AGING | 2023年 / 3卷
关键词
somatic mutation; aging; genome mosaicism; DNA damage; oxidative stress;
D O I
10.3389/fragi.2022.1115408
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
引用
收藏
页数:4
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共 9 条
[1]   Reactive Oxygen Species: Angels and Demons in the Life of a Neuron [J].
Biswas, Kasturi ;
Alexander, Kellianne ;
Francis, Michael M. .
NEUROSCI, 2022, 3 (01) :130-145
[2]   Detecting Somatic Mutations in Normal Cells [J].
Dou, Yanmei ;
Gold, Heather D. ;
Luquette, Lovelace J. ;
Park, Peter J. .
TRENDS IN GENETICS, 2018, 34 (07) :545-557
[3]   Healthy skeletal muscle aging: The role of satellite cells, somatic mutations and exercise [J].
Franco, Irene ;
Fernandez-Gonzalo, Rodrigo ;
Vrtacnik, Peter ;
Lundberg, Tommy R. ;
Eriksson, Maria ;
Gustafsson, Thomas .
INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 346, 2019, 346 :157-200
[4]   Clonal hematopoiesis in human aging and disease [J].
Jaiswal, Siddhartha ;
Ebert, Benjamin L. .
SCIENCE, 2019, 366 (6465) :586-+
[5]   Mutational signatures: emerging concepts, caveats and clinical applications [J].
Koh, Gene ;
Degasperi, Andrea ;
Zou, Xueqing ;
Momen, Sophie ;
Nik-Zainal, Serena .
NATURE REVIEWS CANCER, 2021, 21 (10) :619-637
[6]   Brain Somatic Mutation in Aging and Alzheimer's Disease [J].
Miller, Michael B. ;
Reed, Hannah C. ;
Walsh, Christopher A. .
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 22, 2021, 2021, 22 :239-256
[7]   Mitochondrial DNA mutations in ageing and cancer [J].
Smith, Anna L. M. ;
Whitehall, Julia C. ;
Greaves, Laura C. .
MOLECULAR ONCOLOGY, 2022, 16 (18) :3276-3294
[8]   Somatic variant calling from single-cell DNA sequencing data [J].
Valecha, Monica ;
Posada, David .
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2022, 20 :2978-2985
[9]   Murine models of clonal haematopoiesis to assess mechanisms of cardiovascular disease [J].
Wang, Ying ;
Sano, Soichi ;
Ogawa, Hayato ;
Horitani, Keita ;
Evans, Megan A. ;
Yura, Yoshimitsu ;
Miura-Yura, Emiri ;
Doviak, Heather ;
Walsh, Kenneth .
CARDIOVASCULAR RESEARCH, 2022, 118 (06) :1413-1432